DSM Biomedical Biomedical Materials for Medical Devices

DSM leverages its expertise in life sciences and materials sciences as a global leader in the development of next-generation biomedical materials. DSM brings new material innovation to market, through the development of novel materials-based solutions that meet the present and future needs of the medical device and biopharmaceutical industries.

As a leader in the biomedical materials sector with advanced research and development, manufacturing and materials processing capabilities, DSM develops products that are available for use in short-term and long-term implantable medical devices.

Our growing product portfolio includes:

  • Biostable polyurethanes
  • Hydrophilic and non-biofouling coatings
  • Polymer stabilising technology
  • UHMWPE fibres
  • Resorbable materials
  • Silicone hydrogels

Medical-grade polymers

DSM’s industry-leading medical-grade polymers are:

  • Bionate® PCU
  • BioSpan® SPU
  • CarboSil® TSPCU
  • Elasthane™ TPU
  • PurSil® TSPU

Our polymers have been proven in long-term implants over many years and are available with different properties, such as high strength, flexibility, fatigue resistance and biostability, to meet specific needs.

Specialised coatings for disposable medical devices

Our coatings, ComfortCoat® coating and VitroStealth® non-biofouling coating, are available in specialised formulations, with hydrophilic, antimicrobial, or hemocompatible properties. They are used in disposable devices such as guidewires, catheters and short-term implants used in vascular, neurological, urinary and ophthalmic applications.

DSM Biomedical’s non-biofouling coating reduces unwanted protein absorption and cellular adhesion, which is important for biosensors, insulin pens and insulin pumps, prefilled syringes and cartridges, as well as diagnostic labware.

Ultra-high-molecular-weight polyethylene fibres

Our range of ultra-high-molecular-weight polyethylene (UHMWPE) includes:

  • Dyneema Purity® SGX fibre
  • Dyneema Purity® TG fibre
  • Dyneema Purity® UG and VG fibre

DSM’s fibres are 15 times stronger than steel, by weight, and materials made with these fibres are resistant to fatigue and abrasion, which can contribute to a device’s durability.

They are available in three different grades to meet specific application needs, including improving implant performance in joint repair, or replacement, and reducing the profile of devices for use in minimally invasive procedures without sacrificing strength and durability.

Polymer stabilising technology

Our Hindered Amine Light Stabilizer (HALS) technology offers device manufacturers an option for improving the stability of UHMWPE in orthopedic implants and prolonging their life by strengthening material resistance to oxidation.

Resorbable materials

DSM Biomedical’s proprietary bioresorbable polymers provide the foundation that enables biopharmaceutical companies to formulate implantable drug delivery systems for specific applications.

This technology can assist in creating a platform for delivery of medications to a precise target area in the body, with controlled release from several days to multiple months. Pain, anti-inflammatory and antimicrobial drugs can be delivered for ophthalmic, orthopedic, pain management and vascular treatments.

Silicone hydrogels

DSM technology and ophthalmic expertise were, and continue to be, major contributors to the development of silicone hydrogel contact lenses, helping to create a new generation of super-permeable, comfortable extended-wear contact lenses.

Biocompatible and biostable materials

Our knowledge of the human body allows us to create biocompatible, biostable materials. We will continue to advance biomaterials technology, using bright science to help people lead longer, healthier, more active and brighter lives. Our development efforts focus on three areas of materials interaction with the human body.

  • Bio-passive: such as coatings and polymers that minimise interaction with the body
  • Bioactive: materials that interact with the body, such as those that will be resorbed following full delivery of a medication
  • Interactive: materials that induce some regenerative reaction in the body for angiogenesis or tissue growth

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Press Release

DSM’s VitroStealth Coating Used in Axis-Shield’s Next Generation Afinion Point-of-Care Cartridge

DSM, a global leader in biomedical materials, today announced that its VitroStealth non-biofouling coating is used in Afinion, Axis-Shield's next generation point-of-care diagnostic system. Physicians can use Afinion during the span of an office visit and obtain patient lipid levels within a matter of minutes.

White Papers

Improving Device Performance with Medical-Grade Fibre

Four years before the Wright brothers made history on North Carolina's Kitty Hawk beach in December 1903, Orville and Wilbur discovered a method for controlling an aircraft in flight known as wing-warping that enabled them to improve the amount of lift provided by the wings and helped the plane stay aloft for that first successful flight.

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DSM Biomedical Inc.

2810 Seventh Street

Berkeley

94710

California

United States of America

+1 510 841 8800 +1 510 841 7800 www.dsm.com/medical

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Press Release

9 July 2012

DSM, a global leader in biomedical materials, today announced that its VitroStealth non-biofouling coating is used in Afinion, Axis-Shield's next generation point-of-care diagnostic system. Physicians can use Afinion during the span of an office visit and obtain patient lipid levels within a matter of minutes.

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20 February 2012

DSM, a global leader in biomedical materials sciences, and University Medical Center Utrecht, a leading academic hospital with a renowned experimental facility unit for cardiothoracic interventions, announced that they have entered into a collaboration agreement.

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30 January 2012

DSM, a global leader in biomedical materials sciences, today announced a successful collaboration with medical manufacturer EPflex to launch a new set of guidewires with ComfortCoat hydrophilic coating, a proprietary DSM technology. EPflex will manufacture the guidewires and DSM will provide the coating technology.

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28 November 2011

DSM, a global leader in biomedical materials, today announced that it has signed a joint collaboration agreement with AdeTherapeutics to accelerate the company's scar reduction and pain management product development strategy in neurosurgery, specifically in spine surgery and craniotomy.

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13 November 2011

DSM, a global leader in biomedical materials science, today announced the use of its ComfortCoat hydrophilic coating on the delivery system of CID's new Cre8 Drug Eluting Stent (DES), CE marked 16 July 2011.

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6 November 2011

DSM, a global leader in biomedical materials, and Svelte Medical Systems, a privately held company developing next-generation endovascular therapies, today announced they have entered into a license and supply agreement granting Svelte the right to use DSM's proprietary bioerodible amino acid-based drug carrier in the design of a non-thrombogenic, non-inflammatory drug-eluting stent.

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31 October 2011

DSM, a global leader in biomedical materials, announced that its Dyneema Purity® ultra-highmolecular- weight-polyethylene fiber was selected for use in SpineWorks, LLC's novel Universal Screw Persuader (USP) System.

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15 March 2011

DSM Biomedical, a global leader in biomedical materials science, announced a step forward in its partnership with Ovesco Endoscopy. Ovesco has chosen to exclusively use Dyneema Purity® fiber for the OTSC system due to the material's unique mechanical performance and proven biocompatibility, specifically the combination of high strength, low elongation and high pliability.

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12 January 2011

DSM Dyneema, the inventor and manufacturer of the world's strongest fiber, Dyneema Purity®, announced a partnership with Proxy Biomedical.

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Regional Offices

DSM Biomedical Inc.

2810 Seventh Street

Berkeley

94710

California

United States of America

+1 510 841 8800 +1 510 841 7800 www.dsm.com/medical
DSM Biomedical: Europe

Koestraat 1

6167 RA Geleen

Netherlands

DSM Biomedical

Postbus 43

6130 AA Sittard

Netherlands

DSM Biomedical: Asia Pacific

476 Li Bing Road

201203

Shanghai

China

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