A persistent problem in medicine is the ability to specifically target diseased cells and tissues. Nanomedicine refers to the area of science that combines nanotechnology with drugs or diagnostic molecules to improve the ability to target specific cells or tissues. These materials are produced on a nanoscale level and are safe to introduce into the body.
Applications for nanotechnology in medicine include imaging, diagnosis, or the delivery of drugs that will help medical professionals treat various diseases. In addition to targeted delivery of therapeutics, nanotechnology can also be used to release drugs in a controlled manner. This can result in improved outcomes for patients due to a reduction in toxicity, more efficient delivery of therapeutic molecules, and a longer lifetime of drugs within the body.
Here, GlobalData lists some of the most interesting private companies associated with this theme and summarises their competitive position.
AlfaSigma SpA (Italy)
Alfasigma SpA (Alfasigma) is a pharmaceutical company that develops drugs for various therapies. The company conducts research and development of new drugs through clinical studies conducted in hospitals, universities, and public and private health facilities; offers scientific advice; hosts scientific seminars and conferences; and offers information and updating support for congresses and continuing medical education courses organised by public institutions, universities, scientific societies, and ECM-accredited providers.
It operates through production plants in Alanno, Pomezia, and Sermoneta. The company operates in Milano, Alanno, Pomezia, and Sermoneta, Italy. Alfasigma is headquartered in Bologna, Italy. Nanomedicines approved by the FDA include Adagen, Abelcet, and DepoCyt.
Dompe Farmaceutici SpA (Italy)
Dompe Farmaceutici SpA (Dompe) is a developer of therapeutic solutions that research novel therapies for the treatment of rare and orphan diseases. The company provides product pipeline such as C5aR Antagonists, TRPM8 Blockers pain, TRPM8 Blockers urology, BKB1R Antagonists, CNR2 Agonists and GPR120 Agonists, among others. It offers treatment in the therapeutic areas of respiratory diseases, chronic obstructive pulmonary disease, pulmonary arterial hypertension, cystic fibrosis, osteoarticular solutions, pain therapy and dentistry, among others.
Dompe’s target research areas include respiratory diseases, oncology, diabetology, ophthalmology, organ transplantation, chronic obstructive pulmonary disease and pulmonary arterial hypertension, among others. The company has operations in the US and Albania. Dompe is headquartered in Milan, Italy. Nanomedicines approved by the FDA include Lumason.
GE Healthcare LLC (USA)
GE Healthcare LLC (GE Healthcare), a business unit of General Electric Company, is a global medical device provider that designs, develops, manufactures, and distributes diagnostic imaging and clinical systems; products and services for drug discovery, biopharmaceutical manufacturing and cellular technologies; imaging agents used during medical scanning procedures; and a range of healthcare IT solutions.
GE Healthcare also provides services such as performance improvement and performance solutions services, computerised data management, and remote diagnostics and repair services of medical equipment manufactured by the company and others. The company conducts its operations across the world through subsidiaries and affiliates. GE Healthcare is headquartered in Chicago, Illinois, US. Nanomedicines approved by the FDA include Optison.
Horizon Pharmaceuticals Inc (US)
Horizon Pharmaceuticals Inc (Horizon) is a CDMO company that manufactures, develops, and lifecycle management of blow-fill-seal technology and products. The company provides in- fabrication, house design, and maintenance of BFS machines, aseptic manufacturing and tooling. Its products are used in pharmaceutical sectors such as OTC and Rx unit dose eye drops and gels, inhalation solutions or suspensions, injectable products, emergency eyewash, topical liquids, creams, biotechnology products, gels, and ointments, and oral liquids.
Horizon also provides components to medical devices, reagents in diagnostic products, and components in diagnostic kits. The company offers its packaging solutions for the pharmaceutical, medical, and diagnostic industries. Horizon is headquartered in West Palm Beach, Florida, US. Nanomedicines approved by the FDA include Krystexxa.
Janssen Pharmaceuticals Inc (US)
Janssen Pharmaceuticals Inc (Janssen), a subsidiary of Johnson & Johnson, is a drugs development company. The company offers medicines for an array of health conditions in therapeutic areas of attention deficit hyperactivity disorder, general medicine, mental health, neurologics, pain management, women’s health, and others.
It also offers treatments for acid reflux disease, infectious diseases, bipolar I disorder, schizophrenia, Alzheimer’s disease, epilepsy, and migraine prevention and treatment. Janssen markets its products through a network of distributors across the US. It serves cardiovascular and metabolism, immunology, infectious diseases, vaccines, neuroscience, oncology, and other therapeutic areas. Janssen is headquartered in Titusvi.
This is an edited extract from the Nanotechnology in Medicine report produced by GlobalData Thematic Research.