The medical devices industry continues to be a hotbed of innovation, with activity driven by increased need for homecare, preventative treatments, early diagnosis, reducing patient recovery times and improving outcomes, as well as a growing importance in technologies such as machine learning, augmented reality, 5G, and digitalisation. In the last three years alone, there have been over 450,000 patents filed and granted in the medical devices industry, according to GlobalData’s report on Environment Sustainability in Medical Devices: Bio-active prosthesis sealing.

However, not all innovations are equal and nor do they follow a constant upward trend. Instead, their evolution takes the form of an S-shaped curve that reflects their typical lifecycle from early emergence to accelerating adoption, before finally stabilising and reaching maturity.

Identifying where a particular innovation is on this journey, especially those that are in the emerging and accelerating stages, is essential for understanding their current level of adoption and the likely future trajectory and impact they will have.

150+ innovations will shape the medical devices industry

According to GlobalData’s Technology Foresights, which plots the S-curve for the medical devices industry using innovation intensity models built on over 550,000 patents, there are 150+ innovation areas that will shape the future of the industry.

Within the emerging innovation stage, robotic 3D bio-printing, and 3D printed prosthesis are disruptive technologies that are in the early stages of application and should be tracked closely. Sharps disposal containers, biomedical 3D printing, and tooth 3D printing are some of the accelerating innovation areas, where adoption has been steadily increasing. Among maturing innovation areas are bio-compatible surgical adjuncts and bio-active prosthesis sealing, which are now well established in the industry. 

Innovation S-curve for environmental sustainability in the medical devices industry

Bio-active prosthesis sealing is a key innovation area in environmental sustainability

Bio-active prosthesis sealing refers to a biological seal formed of soft tissue bio-active material surrounding the implant. The seal creates a biological barrier around the prosthesis to guard against infection. Further, these bioactive materials also help induce the regeneration and repair of tissues by producing only specific bonds.

GlobalData’s analysis also uncovers the companies at the forefront of each innovation area and assesses the potential reach and impact of their patenting activity across different applications and geographies.  According to GlobalData, there are 40+ companies, spanning technology vendors, established medical devices companies, and up-and-coming start-ups engaged in the development and application of bio-active prosthesis sealing.

Key players in bio-active prosthesis sealing – a disruptive innovation in the medical devices industry

‘Application diversity’ measures the number of different applications identified for each relevant patent and broadly splits companies into either ‘niche’ or ‘diversified’ innovators.

‘Geographic reach’ refers to the number of different countries each relevant patent is registered in and reflects the breadth of geographic application intended, ranging from ‘global’ to ‘local’.

Patent volumes related to bio-active prosthesis sealing

Company Total patents (2010 - 2021) Premium intelligence on the world's largest companies
AbbVie 55 Unlock company profile
Medtronic 47 Unlock company profile
Merz PharmaaA 29 Unlock company profile
Spotlight Technology Partners 26 Unlock company profile
Croma-Pharma 25 Unlock company profile
Mati Therapeutics 22 Unlock company profile
Orthopaedic Innovation Centre 21 Unlock company profile
Teijin 20 Unlock company profile
Becton Dickinson and Co 15 Unlock company profile
Kona Gold Beverage 14 Unlock company profile
Johnson & Johnson 14 Unlock company profile
P&R 13 Unlock company profile
Hkl Medical 13 Unlock company profile
Ministry of Trade and Industry, Singapore 9 Unlock company profile
Klox Technologies 9 Unlock company profile
QLT Plug Delivery 9 Unlock company profile
Tyco Healthcare Group 9 Unlock company profile
Fujifilm Holdings 7 Unlock company profile
Integra LifeSciences Holdings 7 Unlock company profile
Abbott Laboratories 7 Unlock company profile
Bezwada Biomedical 7 Unlock company profile
Halscion 7 Unlock company profile
Singapore Health Services 6 Unlock company profile
Omeros 5 Unlock company profile
ODIN Biotech Partners 5 Unlock company profile
Reflex Medical 5 Unlock company profile

Source: GlobalData Patent Analytics

EW Healthcare Partners is one of the leading patent filers in bio-active prosthesis sealing. Some other leading patent filers include Johnson & Johnson and Medtronic.

In terms of application diversity, Coloplast leads the pack, followed by QLT Plug Delivery and Mati Therapeutics. By means of geographic reach, Venarum Medical holds the top position, followed by Adient Medical and Micell Technologies in the second and third spots, respectively.

The bioactive sealing material establishes a strong bond between the implant and the tissue, which doesn’t allow any bacteria or toxin to pass through the implant-tissue contact due to the bio-seals' strong sealant integrity. Bio-active sealing materials have garnered a great amount of attention, owing to their stability and integration. For instance, bioactive glass is becoming an important component in the field of dental implants.

To further understand the key themes and technologies disrupting the medical devices industry, access GlobalData’s latest thematic research report on Medical Devices.


GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Patent Analytics tracks patent filings and grants from official offices around the world. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.