Medtronic has been granted a patent for optimized polymeric surfaces designed for implantable medical devices, aimed at reducing inflammatory immune responses. The invention includes a method for using a polyimide composition with specific characteristics, exemplified by an implantable glucose sensor for diabetes management. GlobalData’s report on Medtronic gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Medtronic, Prosthetic cardiac valves was a key innovation area identified from patents. Medtronic's grant share as of June 2024 was 58%. Grant share is based on the ratio of number of grants to total number of patents.
Optimized polymeric surfaces for implantable medical devices
The granted patent US12042284B2 outlines a method aimed at mitigating inflammatory responses associated with implanted medical devices. The method involves the use of an implantable medical device featuring a specialized surface composed of a polyimide material. This surface is characterized by a carbon-to-oxygen ratio exceeding 5 to 1, a hydrophobicity level ranging from 75° to 90°, and a specific topography that includes grooves, wells, or grids with defined peak-to-valley heights. The claims also specify that the device can be implanted in interstitial spaces and can include applications such as glucose sensors.
Additionally, the patent describes a polymer composition that shares the same surface characteristics as the implantable medical device. Notably, when RAW264.7 macrophages come into contact with this surface, they are prompted to differentiate into an anti-inflammatory (M2) phenotype. This differentiation is significant as it suggests a potential mechanism for reducing inflammation around the implant, thereby enhancing biocompatibility and overall performance of the medical device in vivo.
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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.
