US-based medical device company Bruker has introduced two new preclinical imaging systems at the World Molecular Imaging Congress (WMIC) 2016.

The new systems are designed for routine imaging with better performance and convenience, and to probe into causes, progression, as well as the diagnosis and treatment of a disease.

Bruker’s new SkyScan 1276 microCT (X-ray micro-Computed Tomography) features better resolution, speed, accessibility and other innovations to promote an improved in vivo scanning of small laboratory animals and of in-vitro biological samples in preclinical studies.

The SkyScan 1276 is characterised by continuously variable magnification, including a smallest pixel size of 2.8µm, and a shortest scanning cycle of 3.9 seconds which allows the researchers an access to highest-quality images at higher throughput.

It offers rapid helical scanning and reconstructs images up to 8000×8000 pixels per slice using the InstaRecon technology.

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Its user-friendly touchscreen gives the researcher easy system control, they can also view and share images on any iOS or android mobile device.

Bruker is also introducing its Silicon photomultiplier (SiPM) PET insert for simultaneous PET/MRI (Positron Emission Tomography / Magnetic Resonance Imaging) investigations in mice and rats.

This PET insert is compatible with MRI systems up to 15.2 Tesla and allows simultaneous measurements to correlate PET and MRI data in space and time, in order to examine tracer kinetics, therapeutic agent distribution and animal physiology.

The new PET insert has been installed in a 7 Tesla 30cm magnet in a Bruker preclinical MRI system at the University of Leuven, Belgium.

"The simultaneous measurements offered us high-research throughput, and its unique Full Field Accuracy (FFA) facilitates consistent quantification across the entire field-of-view."

University of Leuven faculty of medicine, department of imaging and pathology professor Dr Uwe Himmelreich said: “The new Bruker SiPM PET insert enables us to produce improved PET resolution through MRI-based motion correction, and to guide external interventions in real time.

“The simultaneous measurements offered us high-research throughput, and its unique Full Field Accuracy (FFA) facilitates consistent quantification across the entire field-of-view.

“With 0.7mm resolution and 12% sensitivity, this high-performance PET insert provides us with a complete solution that seamlessly integrates into the workflows and software of our existing Bruker MRI system.”


Image: Bruker’s new SkyScan 1276 microCT. Photo: courtesy of Bruker.