Penumbra’s launch of the Ruby® XL peripheral embolization coil system won the Innovation award in the Vascular Solutions category and the Product Launches award in the Endovascular Devices category in the 2025 Medical Device Network Excellence Awards. Penumbra won the awards for advancing embolization technology through the versatile new coil system.
The Medical Device Network Excellence Awards honor the most significant achievements and innovations in the medical devices industry. Powered by GlobalData’s business intelligence, the Awards recognize the people and companies leading positive change and shaping the future of the industry.
Go deeper with GlobalData
Discover B2B Marketing That Performs
Combine business intelligence and editorial excellence to reach engaged professionals across 36 leading media platforms.
The Ruby XL System introduces new options for peripheral embolization, providing clinicians with tools to address complex vascular challenges.
Advancements in embolization: Penumbra’s innovative vascular solution
Penumbra’s Ruby XL System addresses several persistent challenges in vascular embolization. Notably, the system features coils that are both the largest and longest currently available, yet remain exceptionally soft. This combination is useful for treating large or unusually shaped blood vessels such as wide-necked aneurysms or high-flow vascular segments that have traditionally been difficult to manage with standard coils. With a primary diameter of .030″ and lengths extending up to 70cm, the Ruby XL System allows physicians to treat cases that might otherwise require multiple devices or be unsuitable for coil embolization.
A key distinction of the Ruby XL System is its softness and mechanical occlusion design, achieved without fibers or hydrogel. Fibered or gel-based coils may increase the stiffness of a coil and inhibit delivery, particularly in tortuous anatomy. Ruby XL instead builds occlusion through large-volume mechanical packing, thus creating a stable, durable coil mass over time. By relying on mechanical occlusion rather than physiologic clot formation, Ruby XL is designed to support smoother navigation, more controlled deployment, and consistent long-term durability across a wide range of anatomies.
The system brings together three different coil types: Ruby XL, POD® XL, and Packing Coil XL—each designed for a specific function. For instance, Ruby XL is intended for framing large aneurysms, POD XL provides anchoring in high-flow vessels, and Packing Coil XL is used for dense filling and adaptability. This modular approach means clinicians can select the best combination for each patient, which can help streamline procedures and potentially improve outcomes.
One of the more innovative aspects is the Packing Coil XL’s dynamic liquid metal wave shape. This feature allows the coil to adjust in real time to the vessel’s contours, which is especially valuable in vessels that are twisted or vary in diameter.
As a result, physicians may need fewer device exchanges and can achieve a more customized fit. Additionally, because the Ruby XL System delivers up to three times more volume per coil than some other products, it may reduce the total number of coils needed, potentially shortening procedures and minimizing device handling.
Expanding clinical possibilities in endovascular care
Since its introduction, the Ruby XL System has influenced the endovascular device market, particularly for peripheral embolization. It is available in wide range of coil sizes and lengths. With diameters up to 40mm and lengths reaching 70cm, the system supports a variety of clinical scenarios—from small vessel occlusions to large, high-flow vascular territories. This flexibility helps interventionalists who often encounter unpredictable anatomy and need devices that can adapt to different situations.
Another practical advantage is the system’s compatibility with standard .035”+ diagnostic catheters. This means that most interventional suites can use the Ruby XL System without needing to purchase or learn new delivery equipment. Such compatibility can simplify inventory management and speed up the adoption process, as clinicians can incorporate the system into their existing workflows with minimal disruption.
The design also addresses efficiency and safety. By delivering more coil volume with each device, the Ruby XL System can reduce the number of coils required for effective vessel occlusion. This can lead to shorter procedures, less radiation exposure for both patients and staff, and potentially lower overall costs. For example, in cases involving large aneurysms or high-flow vessels, where traditional coils might require several deployments, the Ruby® XL System allows for more efficient packing and fewer device exchanges.
The POD XL coil’s three-in-one occlusion technology—anchoring, framing, and dense filling—further enhances procedural control. This design helps clinicians achieve secure placement in high-flow vessels, create a stable frame for packing, and ensure dense occlusion, all with a single device. Such features are helpful in challenging cases where stability and precision are essential.
By addressing these practical and clinical needs, the Ruby XL System demonstrates Penumbra’s focus on developing solutions that reflect the realities of endovascular practice. Its introduction has expanded the options available for peripheral embolization, giving clinicians new strategies for managing complex vascular conditions.
Company Profile
Penumbra, Inc., the world’s leading thrombectomy and embolization company, is focused on developing the most innovative technologies for challenging medical conditions such as ischemic stroke, venous thromboembolism such as pulmonary embolism, and acute limb ischemia. Its broad portfolio, which includes computer assisted vacuum thrombectomy (CAVT), centers on removing blood clots from head-to-toe with speed, safety and simplicity. By pioneering these innovations, Penumbra supports healthcare providers, hospitals and clinics in more than 100 countries, working to improve patient outcomes and quality of life.
Links:
