Bio-Rad Laboratories. has filed a patent for a system and method for target material capture. The method involves capturing target cells and particles in an array of wells, achieving a desired state, and retaining intercellular material. The claim focuses on capturing target nucleic acid material and delivering reagents for processing. GlobalData’s report on Bio-Rad Laboratories gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Bio-Rad Laboratories, Laboratory automation robots was a key innovation area identified from patents. Bio-Rad Laboratories's grant share as of January 2024 was 51%. Grant share is based on the ratio of number of grants to total number of patents.
Target material capture system and method
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The filed patent (Publication Number: US20230407372A1) describes a method that involves capturing target nucleic acid material from a biological sample across an array of wells on a substrate. The method aims to achieve a specific capture state for each well in the array, ensuring that each well contains a specific target from a set of targets without any contamination. A sequence of reagents, including water, is delivered to process the target nucleic acid material in each well. To prevent leakage and cross-contamination between wells, at least one of the reagents is displaced with a liquid immiscible with water, effectively partitioning each well and maintaining the integrity of the samples.
This innovative method offers a solution to the challenge of processing target nucleic acid material in a high-throughput manner while minimizing the risk of contamination between samples. By utilizing a liquid immiscible with water to partition the wells, the method ensures that each well remains isolated from adjacent wells, reducing the potential for leakage and maintaining the integrity of the samples throughout the processing steps. This approach not only improves the efficiency of processing biological samples but also enhances the reliability and accuracy of the results obtained. Overall, the patent presents a novel and practical technique for handling target nucleic acid material in a controlled and precise manner, with potential applications in various fields such as research, diagnostics, and personalized medicine.
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