Bio-Techne‘s patent involves systems and methods for analyzing gene delivery particles in samples to determine their quality and state. By establishing relationships between nucleic acid content and particle states, the technology can predict the proportion of particles in different states in test samples. GlobalData’s report on Bio-Techne gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Bio-Techne, Peptide pharmacophores was a key innovation area identified from patents. Bio-Techne's grant share as of January 2024 was 40%. Grant share is based on the ratio of number of grants to total number of patents.
Method for analyzing gene delivery particles in samples
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A recently granted patent (Publication Number: US11827946B2) outlines a method for analyzing viral vectors in a test sample. The method involves receiving two test signals associated with the sample, one linked to nucleic acid (NA) in a subset of viral vectors and the other to protein in another subset. By identifying specific features in these signals and comparing them to standard values obtained from known samples, the proportion of viral vectors in a full state can be determined. This innovative approach allows for a detailed analysis of the viral vectors present in the sample, providing valuable insights into their composition and state.
Furthermore, the method includes transmitting the determined proportion to an output device, enabling easy visualization of the results. By utilizing electrophoretic separation techniques and miniaturized fluidic paths, the method ensures precise separation and analysis of the viral vectors based on their properties. The patent also details the calculation of NA and protein quantities in the sample, as well as the use of standard curves to establish relationships between these quantities and the proportion of viral vectors in a full state. Overall, this patented method offers a comprehensive and efficient way to assess viral vector composition and state, with potential applications in various fields such as biotechnology and pharmaceuticals.
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