Biodesix‘s patent involves methods to identify biomarker proteins for diagnosing and monitoring lung conditions. The patent also includes a method to treat pulmonary nodules by measuring protein levels in blood samples, determining a lung cancer probability score, and treating subjects with scores indicating cancer. GlobalData’s report on Biodesix gives a 360-degree view of the company including its patenting strategy. Buy the report here.
According to GlobalData’s company profile on Biodesix, AI-assisted drug screening was a key innovation area identified from patents. Biodesix's grant share as of February 2024 was 42%. Grant share is based on the ratio of number of grants to total number of patents.
Diagnosing and treating lung cancer using biomarker proteins
A recently granted patent (Publication Number: US11913957B2) discloses a method for treating a pulmonary nodule in a subject by measuring the expression levels of specific proteins in a blood sample. The method involves performing an immunoassay to measure the levels of proteins such as LG3BP and C163A, determining a probability of lung cancer score based on these measurements, and treating the subject if the score meets a predetermined threshold through surgery, chemotherapy, radiotherapy, or a combination of these treatments.
The patent claims also include details such as the use of an enzyme-linked immunosorbent assay (ELISA) for the immunoassay, the inclusion of a panel of proteins beyond LG3BP and C163A, the specific diameter range of the pulmonary nodule being treated, the age group and risk factors of the subject, and the incorporation of clinical assessments like pulmonary imaging and biopsies. The method aims to provide a comprehensive approach to diagnosing and treating pulmonary nodules, particularly in subjects at risk of developing lung cancer, by utilizing specific protein markers and a combination of medical interventions based on the probability score derived from the immunoassay results.
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