DexCom has patented a system for continuous in vivo analyte detection using sensors with a particle-containing domain. The system includes a continuous analyte sensor with a membrane containing an enzyme domain and a particle-containing domain for accurate measurements. The sensor electronics generate signals associated with the analyte in the host. GlobalData’s report on DexCom gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on DexCom, Medical data analysis was a key innovation area identified from patents. DexCom's grant share as of February 2024 was 45%. Grant share is based on the ratio of number of grants to total number of patents.

Continuous analyte measurement system with particle-containing domain for implantation

Source: United States Patent and Trademark Office (USPTO). Credit: DexCom Inc

A recently granted patent (Publication Number: US11918354B2) discloses a system for continuous in vivo detection of an analyte, such as glucose, in a host. The system includes a continuous analyte sensor with a working electrode containing an electroactive surface and a membrane with an enzyme domain and a particle-containing domain. The particle-containing domain, comprising a conductive component dispersed in a non-conductive component, is designed to electrochemically react with interfering species. The sensor electronics generate a signal associated with the analyte in the host, providing real-time monitoring capabilities.

The system's design allows for efficient detection of the analyte by utilizing a combination of materials for the conductive component, including platinum, graphite, silver, and conductive polymers. The method involves implanting the sensor into the host's tissue, allowing the membrane to facilitate the diffusion of the analyte. By applying a potential to the particle-containing domain, the system can accurately detect the concentration of the analyte. Additionally, the method includes electrochemically reacting the particle-containing domain with interfering species, either by oxidizing or reducing them, to ensure precise and reliable measurements. Overall, this patented system offers a sophisticated and effective solution for continuous in vivo monitoring of analytes, with a particular focus on glucose detection.

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.