OPKO Health. has filed a patent for antigen binding polypeptide complexes with specific structural features. The patent includes polynucleotides, vectors, cells, pharmaceutical compositions, and methods of using these complexes. The claim outlines the detailed structures of the polypeptides involved in the complex. GlobalData’s report on OPKO Health gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on OPKO Health, Peptide pharmacophores was a key innovation area identified from patents. OPKO Health's grant share as of January 2024 was 51%. Grant share is based on the ratio of number of grants to total number of patents.

Antibody complexes with specific structural features

Source: United States Patent and Trademark Office (USPTO). Credit: OPKO Health Inc

The patent application (Publication Number: US20240034808A1) describes an antigen binding polypeptide complex consisting of three polypeptides - a first, second, and third polypeptide. The first polypeptide has a specific structure, while the second and third polypeptides have distinct structures as well. The complex is designed to bind to specific targets such as CD3, tumor-associated antigens (TAAs), or immune stimulatory receptors. The polypeptides contain various regions and linkers, each serving a specific function in the binding process. The patent also covers modifications to the Fc region, hinge region, and specific amino acid sequences within the polypeptides to enhance binding efficacy.

Furthermore, the patent application includes claims related to the length and composition of amino acid linkers, as well as specific sequences within the polypeptides that are crucial for binding to target molecules. The patent also outlines the use of the antigen binding polypeptide complex in inducing or enhancing immune responses and overcoming cancer-mediated immune suppression. Additionally, the patent covers the use of the complex in pharmaceutical compositions for therapeutic purposes. Overall, the patent application provides a detailed description of a novel antigen binding polypeptide complex with potential applications in immunotherapy and cancer treatment.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies