Ortho Clinical Diagnostics has patented an assay device with a unique design to control sample volume. The device includes specific zones for sample addition, reagent addition, detection, and wicking, ensuring precise sample size control. This innovation aims to enhance accuracy in diagnostic testing. GlobalData’s report on Ortho Clinical Diagnostics gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Ortho Clinical Diagnostics, was a key innovation area identified from patents. Ortho Clinical Diagnostics's grant share as of February 2024 was 65%. Grant share is based on the ratio of number of grants to total number of patents.

Assay device with interrupting wash for sample volume control

Source: United States Patent and Trademark Office (USPTO). Credit: Ortho Clinical Diagnostics Holdings Plc

A recently granted patent (Publication Number: US11921107B2) discloses an innovative assay device designed for efficient detection of analytes in liquid samples. The device comprises a liquid sample addition zone, a reagent zone, a detection zone with capture elements, and a wicking zone to facilitate fluid flow. Notably, the device includes a reagent addition zone strategically positioned along the fluid flow path to control the sample size and interrupt the flow of the sample when necessary. This feature ensures precise and controlled movement of the liquid sample through the device, enhancing the accuracy of the assay results.

Furthermore, the patent claims detail a method for performing assays using the device, involving the addition of a liquid sample and reagent to specific zones, followed by capillary-driven movement of the sample through the device. The method includes steps such as detecting the analyte of interest in the detection zone and flowing the sample into the wicking zone. Additionally, the method incorporates the use of labeled reagent materials and capture elements for efficient detection and generation of signals. Overall, the patented device and method offer a comprehensive solution for conducting assays on liquid samples, ensuring reliable and accurate results through precise control of sample movement and detection processes.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.