Rapid Micro Biosystems has filed a patent for a cell culturing device that can capture and culture microorganisms. The device includes a nutrient media with a flat growth area, where microorganisms can grow. Samples can be collected by contacting the device with environmental samples or filtering a sample through a membrane. The device allows for the detection of microorganisms, which can be imaged digitally or with film. GlobalData’s report on Rapid Micro Biosystems gives a 360-degree view of the company including its patenting strategy. Buy the report here.
According to GlobalData’s company profile on Rapid Micro Biosystems, optoelectronic biosensors was a key innovation area identified from patents. Rapid Micro Biosystems's grant share as of September 2023 was 35%. Grant share is based on the ratio of number of grants to total number of patents.
The patent is filed for a cell culturing device
A recently filed patent (Publication Number: US20230272447A1) describes a cell culturing device that aims to monitor the presence and growth of microorganisms in a sample. The device consists of a base containing nutrient media for microorganisms, with a flat growth area raised above the base. A film overlays the nutrient media, sloping from the edge of the growth area to the base, and has an opening to expose a portion of the growth area. A lid mates with the base to cover the membrane and the nutrient media.
The device also includes a porous membrane in contact with the exposed growth area, which has through holes that expose fluorescent nutrient media, plastic, or printed material. The membrane is described as a mixed cellulose ester membrane that is substantially non-radiative and non-reflective or black. Additionally, the device may include a fiducial mark outside the growth area, which can be made of radiative plastic, printed fluorescent material, or embossed fluorescent material.
The lid of the device is made of optically clear material, allowing for imaging of the growth area. It also prevents contamination by microorganisms through an air gap separating it from the membrane. The base and lid are designed to prevent rotation of the base relative to the lid by more than about 50 µm.
The patent also describes a method for monitoring the presence of microorganisms using the device. The method involves filtering a sample through the porous membrane, placing the membrane on the growth area, incubating the device to allow growth of microorganisms, and determining the extent of growth, which can be done through optical imaging. The image can be analyzed to quantify the number of microorganisms, and the process can be repeated to identify growing colonies.
Overall, this patent presents a cell culturing device and method that allows for efficient monitoring of microorganisms in a sample. The device's design and features, such as the porous membrane, fiducial mark, and optically clear lid, contribute to accurate and reliable monitoring of microorganism growth.