Netherlands-based firm Polyganics has received funding from the European Fund for Regional Development (ERDF) by the European Union (EU) for further development of its dura sealant patch.

Made using the firm’s bioresorbable polymers, the sealant patch is being developed as a suitable dressing to reseal the outer membrane (dura) surrounding the brain.

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The patch is intended to decrease leakage of cerebrospinal fluid (CSF) following brain surgery and is designed to stimulate tissue regeneration.

After the membrane has healed, the device undergoes natural and safe degradation within the body.

The firm intends to use the €1.2m grant to support clinical validation of the patch and plans to launch clinical trials early next year to evaluate safety and performance in humans.

“The firm intends to use the €1.2m grant to support clinical validation of the patch and plans to launch clinical trials early next year to evaluate safety and performance in humans.”

In partnership with the Brain Technology Institute (BTI) and Syncom, Polyganics has successfully completed studies of the sealant patch in animals.

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Polyganics CEO Rudy Mareel said: “We are hugely appreciative to the EU, as well as the city and province of Groningen for their support in progressing the device into the next phase of its development.

“The grant is a great recognition of the potential of this application of our synthetic polymers, and we are pleased to have benefited from the skills and expertise of both the BTI and Syncom in its development.

“The work has important implications for improved recovery following brain surgery, including helping to prevent potentially fatal complications such as meningitis.”

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