Researchers at Rutgers Robert Wood Johnson Medical School (Rutgers RWJMS) and Robert Wood Johnson University Hospital (RWJUH) have found new biological markers, or indicators, for the early detection of heart disease.

The new, breakthrough ultrasonic imaging technique can identify microscopic changes that occur in heart structure and function.

Discover B2B Marketing That Performs

Combine business intelligence and editorial excellence to reach engaged professionals across 36 leading media platforms.

Find out more

These changes may help detect early heart disease by leveraging miniaturised ultrasound devices that can be carried in the pocket.

The researchers used artificial intelligence (AI) modelling methods to analyse pixel-based patterns in echocardiogram images and develop interpretations of cardiac conditions that may lead to heart failure.

Using a mouse model of heart failure, they later discovered that these patterns arise from microscopic changes in heart muscle geometry.

Additionally, the researchers established that the new biological markers, or indicators, can help physicians detect cardiac problems earlier and provide important information for helping to plan the appropriate treatment.

GlobalData Strategic Intelligence

US Tariffs are shifting - will you react or anticipate?

Don’t let policy changes catch you off guard. Stay proactive with real-time data and expert analysis.

By GlobalData

RWJMS Cardiovascular Disease and Hypertension Division chief Dr Partho Sengupta said: “By establishing and analysing patterns of pixels obtained from the sample echocardiogram images, we were able to predict presence of heart conditions that can cause heart failure.

“Identifying changes in the heart muscle or cardiovascular function earlier can lead to more proactive interventions and the prevention of serious complications.”

He also said that the new biomarker can be applied to any existing cardiac ultrasound device, such as advanced, miniature hand-held point-of-care ultrasound technology.

Dr Sengupta added: “This has the potential to give more people access to in-depth, expert analysis in a broad range of settings, leading to faster intervention and prevention of serious cardiac disease.”

Medical Device Network Excellence Awards - Nominations Closed

Nominations are now closed for the Medical Device Network Excellence Awards. A big thanks to all the organisations that entered – your response has been outstanding, showcasing exceptional innovation, leadership, and impact

Excellence in Action
HemoSonics has won the 2025 Marketing Award for its impactful promotion of theQuantra Hemostasis System and leadership in blood management education. See how targeted campaigns, thought leadership content, and hands on clinician training are accelerating Quantra’s market traction and shaping the future of hemostasis testing.

Discover the Impact