New quantitative analysis of NeuraCeq PET will aid identification of amyloid plaques in the brain. Credit: peterschreiber.media / Shutterstock.com.

Koneksa has teamed up with Beacon Biosignals for a clinical trial to assess the integration of the latter’s at-home electroencephalogram (EEG) into its Neuroscience Solution Toolkit.

The Beacon Platform unlocks longitudinal EEG technology and leverages machine-learning algorithms to increase insights into brain activity, helping sponsors to gain comprehensive data analysis and data visualisation capabilities.

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Referred to as LEARNS, the Koneksa-sponsored, syndicated and observational study has been designed for identifying biomarkers and determining the validity and usability measures of sleep and neurologic disorders collected using smartphones, at-home EEG and wearables.

The trial will compare the Koneksa neuroscience solution and the Beacon Biosignals platform for at-home EEG, with in-clinic polysomnography, in neurological and sleep disorders.

Parkinson’s, Alzheimer’s and Huntington’s, as well as mild cognitive impairment, obstructive sleep apnoea and narcolepsy are the current cohorts in the LEARNS study.

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Koneksa chief medical officer John Wagner said: “Beacon’s mobile EEG will join more than a dozen digital health technologies that are already integrated into the Koneksa solution.”

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The trial will measure the validity of smartphone-based motor, speech and cognitive assessments against gold-standard tools.

Furthermore, it will evaluate whether assessment combinations hold the potential to detect diagnostic features at the cohort diagnostic boundary.

Beacon Biosignals co-founder and CEO Dr Jacob Donoghue said: “With our shared science-first ethos, we are united in our relentless pursuit to develop cutting-edge tools that revolutionise drug development and accelerate the delivery of life-changing therapies to patients.”