Agilent Technologies. has filed a patent for a degasser designed to remove gas from a mobile phase in chromatography. The degasser chamber includes a delimiting unit to separate spaces with different vapor pressures, along with a suction unit to remove gas that passed through the degassing membrane. GlobalData’s report on Agilent Technologies gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Agilent Technologies, Microfluidics automation was a key innovation area identified from patents. Agilent Technologies's grant share as of January 2024 was 52%. Grant share is based on the ratio of number of grants to total number of patents.

Degasser for removing gas from mobile phase in chromatography

Source: United States Patent and Trademark Office (USPTO). Credit: Agilent Technologies Inc

The patent application (Publication Number: US20240033658A1) describes a degasser for degassing a mobile phase used in sample separation devices. The degasser includes a degasser chamber with a degasser volume for receiving a degassing membrane, a delimiting unit to separate spaces with different vapor pressures, and a suction unit to remove gas that passed through the membrane. Additionally, the degasser may have an associated gas supply unit to maintain pressure balance and features for adjusting fluidic restrictions in the suction unit. The invention aims to efficiently remove gas from the mobile phase to improve sample separation processes.

Furthermore, the patent application details methods for degassing the mobile phase using the described degasser. By creating spaces with varying vapor pressures and utilizing suction units and associated gas supply units, the methods ensure effective degassing of the mobile phase. The inclusion of restriction adjustment units allows for fine-tuning the degassing process. These methods are designed to enhance the performance of sample separation devices, particularly those operating at high pressures, such as liquid chromatography or HPLC devices. Overall, the invention offers a comprehensive solution for degassing mobile phases in sample separation applications, potentially improving the accuracy and efficiency of analytical processes.

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