AxoGen. has filed a patent for a dehydrated multi-layer amnion product with at least four layers and less than ten layers, including chorion membrane and amnion layers. The product features specific compositions for each layer, offering potential benefits in tissue regeneration and wound healing. GlobalData’s report on AxoGen gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on AxoGen, AI-assisted MRI was a key innovation area identified from patents. AxoGen's grant share as of January 2024 was 29%. Grant share is based on the ratio of number of grants to total number of patents.

Multi-layer amnion product for medical applications

Source: United States Patent and Trademark Office (USPTO). Credit: AxoGen Inc

A recently filed patent (Publication Number: US20240009348A1) describes a dehydrated multi-layer amnion product consisting of at least four layers and less than ten layers, including at least one chorion membrane layer and at least two amnion layers. Each amnion layer is composed of an epithelial layer, a basement membrane, and a fibroblast layer, while each chorion layer comprises a reticular layer and a basement membrane. The product can be obtained from either human or non-human sources and is created by washing, cutting, overlaying, drying, and sterilizing the layers to form a dehydrated sheet. The method involves using specific cleaning solutions, orienting the layers in different arrangements based on the desired number of layers, and utilizing e-beam radiation for sterilization.

The patent also details a method for making a multi-layer amnion product specifically from amnion layers obtained from an amniotic sac. This method involves washing, cutting, overlaying, drying, and sterilizing the layers to form a dehydrated sheet with at least four layers and less than ten layers. The outermost amnion layers are oriented so that the epithelial layer faces outward, and the product can consist of five, six, or seven layers. The orientation of adjacent amnion layers is specified to ensure the proper alignment of the epithelial and fibroblast layers. Overall, the patent provides a comprehensive guide for creating a dehydrated multi-layer amnion product with specific layer compositions and orientations, suitable for various applications in the medical field.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies