BioNano Genomics. has been granted a patent for integrated analysis devices featuring macroscale and nanoscale dimensions. The devices are designed to minimize background signals and fluorophore quenching. The patent also includes methods for fabricating these devices, which utilize a unique fluid transport system with branched and nanochannel regions. GlobalData’s report on BioNano Genomics gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on BioNano Genomics, Microfluidic devices was a key innovation area identified from patents. BioNano Genomics's grant share as of July 2024 was 33%. Grant share is based on the ratio of number of grants to total number of patents.
Integrated analysis devices with nanoscale fluid transport channels
The patent US12071340B2 outlines a method for fabricating an analysis device that features a unique design for fluid transport. The method involves bonding two substrates to create an enclosed conduit, which includes a branched channel region and a nanochannel analysis region. The branched channel region consists of a primary channel with a cross-sectional dimension ranging from approximately 10 nm to 10,000 nm, along with at least two secondary channels that maintain a constant flow rate by having a total cross-sectional area equal to that of the primary channel. The design incorporates a stacked array of channels with progressively reduced dimensions and is characterized by a specific ratio of cross-sectional dimensions between the primary and secondary channels, which ranges from 100 to 10,000.
Additionally, the patent specifies various materials that can be used for the substrates, including silicon and other semiconductor materials, as well as dielectrics and metals. The bonding process may involve techniques such as anodic or thermal bonding. The design also includes features like splitter structures that divide the primary channel into secondary channels, with specific angles and overhangs to optimize fluid flow. The method allows for the incorporation of thin films to enhance bonding and provide electrical insulation within the conduit. Overall, the patent presents a comprehensive approach to creating advanced analysis devices with precise fluid transport capabilities.
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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.
