Cerus. has filed a patent for detecting antibodies in biological samples, especially in patients treated with pathogen-inactivating compounds. The patent includes compositions, methods, kits, and systems for this purpose. GlobalData’s report on Cerus gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Cerus, Automatic disinfection robots was a key innovation area identified from patents. Cerus's grant share as of January 2024 was 48%. Grant share is based on the ratio of number of grants to total number of patents.
Detecting antibodies in biological samples against pathogen-inactivating compound treated rbcs
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The patent application (Publication Number: US20230408490A1) describes a method for testing a sample for the presence of antibodies reactive to pathogen-inactivated red blood cells. The method involves providing a sample from a potential recipient, contacting the sample with red blood cells bound with a specific moiety, and comparing the binding between antibodies in the sample and the surface-bound moiety with a reference to determine the presence of reactive antibodies. The surface-bound moiety can be a non-frangible analog of S-303 or a salt thereof, present at a specific loading level per red blood cell.
Furthermore, the patent application also discloses a method for providing a red blood cell transfusion to a patient treated with pathogen-inactivating compounds. This method includes testing a sample from the patient for the presence of antibodies as described earlier, determining the binding levels compared to a reference, and providing the transfusion based on the binding results. The surface-bound moiety in this method can also be a non-frangible analog of S-303 or a salt thereof, with specific chemical properties outlined in the claims. These methods aim to ensure the safety and efficacy of red blood cell transfusions by detecting antibodies reactive to pathogen-inactivated red blood cells before administering the transfusion to the patient.
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