DermTech has been granted a patent for a non-invasive method of analyzing skin samples for diagnosing melanoma and solar lentigo. The method involves obtaining a skin sample using adhesive tape with a demarcation indicating the region to be processed, and analyzing target genes in the removed region. This method could potentially improve the accuracy and efficiency of diagnosing skin conditions. GlobalData’s report on DermTech gives a 360-degree view of the company including its patenting strategy. Buy the report here.
According to GlobalData’s company profile on DermTech, Predictive cancer diagnosis models was a key innovation area identified from patents. DermTech's grant share as of September 2023 was 21%. Grant share is based on the ratio of number of grants to total number of patents.
Non-invasive analysis of skin sample using adhesive tape
A recently granted patent (Publication Number: US11753687B2) describes a method for non-invasive analysis of a skin sample using adhesive tape. The method involves obtaining a skin sample collected using adhesive tape that has an adhesive matrix on one surface and a demarcation indicative of a region to be processed. The demarcated region is then removed from the collection area, and one or more target genes in the removed region are analyzed.
The demarcation on the adhesive tape can be representative of an outline of a skin lesion, approximately 1 millimeter from the outline. It can be created using a surgical skin marker or a water-soluble marker. The collection area may be made of transparent material, and multiple adhesive tapes can be used to collect the skin sample.
The analysis of the removed region involves the detection of RNA and/or DNA. The method can also derive information related to a disease based on the quantified expression levels of the target genes. This disease can include cancer, and the derived information may include the identification of a disease state, the likelihood of treatment success, the identification of disease progression, or the identification of a disease stage.
In addition to the method for non-invasive analysis, the patent also describes a method for non-invasive collection and analysis of a skin sample. This method involves receiving an adhesive skin sample collection kit that includes adhesive tape with an adhesive matrix and a demarcation indicative of a region to be processed. The method further includes quantifying expression levels of one or more target genes in the skin sample.
The demarcation in this method can also be representative of an outline of a skin lesion, approximately 1 millimeter from the outline. An adhesive strip is provided, onto which the adhesive matrix with the skin sample is placed. The adhesive strip can be stored at -20 degrees Celsius prior to analysis. The demarcation can be created using a surgical skin marker or a water-soluble marker.
Overall, this patent presents a method for non-invasive analysis and collection of skin samples using adhesive tape, with potential applications in disease diagnosis and monitoring, particularly in the field of dermatology.