Guerbet has been granted a patent for a complex of formula (II), consisting of a diastereoisomeric excess of isomers II-RRR and II-SSS. The patent also covers a method for preparing this complex and its use in medical imaging compositions. GlobalData’s report on Guerbet gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Guerbet, Nanorobotics was a key innovation area identified from patents. Guerbet's grant share as of July 2024 was 55%. Grant share is based on the ratio of number of grants to total number of patents.
The granted patent US12064487B2 outlines a method for medical imaging that involves administering a specific composition to a subject. This composition includes a complex defined by formula (II) and may contain a free macrocyclic ligand, such as DOTA or its derivatives, in concentrations ranging from 0.01 to 1.5 mol·L-1. The claims specify that the purity of the complex should exceed 90%, with options for higher purity levels of 95% and 97%, as determined by chromatography. Additionally, the composition can include isomers II-RRR and II-SSS in a specified ratio, and the pH of the composition is maintained between 4.5 and 8.5.
Further claims detail the inclusion of various buffers, such as Tris and HEPES, to stabilize the composition. The patent emphasizes the importance of the concentration of the complex and the purity of the components, which are critical for effective medical imaging. Specifically, when DOTA is used as the free macrocyclic ligand, the concentration of the complex is suggested to be between 0.3 and 0.6 mol·L-1, with a preferred pH range of 6.5 to 8. These specifications aim to enhance the efficacy and safety of the imaging method, providing a structured approach to the formulation of the imaging composition.
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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.
