Integer has patented a method for manufacturing implantable medical leads using MP35N wire. The process involves electropolishing to remove surface imperfections, specifically chevrons, enhancing the wire’s durability and reducing the risk of premature fatigue failure during its operational lifespan. GlobalData’s report on Integer gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Integer, Cardiac stimulation implants was a key innovation area identified from patents. Integer's grant share as of June 2024 was 67%. Grant share is based on the ratio of number of grants to total number of patents.

Method for electropolishing mp35n wire for medical leads

Source: United States Patent and Trademark Office (USPTO). Credit: Integer Holdings Corp

The patent US12043915B2 outlines a method for manufacturing an implantable medical lead using MP35N wire, which is an alloy composed of 35% cobalt, 35% nickel, 20% chromium, and 10% molybdenum by weight. The process begins with providing a length of MP35N wire that has a specific surface layer characterized by a distribution of chevrons, measuring between 0.00010 inches and 0.00035 inches. The wire undergoes electropolishing to remove this surface layer, resulting in a treated wire with a reduced diameter that is free of chevrons. The final step involves winding the treated wire into a coil to form the implantable medical lead, ensuring that the entire length of the wire in the lead maintains the new diameter.

Additionally, the patent details variations of the method, including the option to use solid MP35N wire or MP35N wire that is cladding an electrically conductive metal core, with possible materials for the core including silver, gold, tantalum, platinum, and titanium. The electropolishing process is further specified, including the use of a sulfuric acid solution mixed with water or ethylene glycol, and the application of an electrical potential with a current density ranging from 50 to 600 amps per square foot. The method also allows for the coating of the treated wire with an insulative material before winding, and the final assembly includes attaching a proximal electrical connector and an electrode for interaction with body tissue, thereby enhancing the functionality of the implantable medical lead.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.