Laboratory Corp of America Holdings patented a method for rapid detection of Salmonella spp. in powdered infant formula using a genetically modified bacteriophage. The method involves incubating the sample with the bacteriophage and detecting the indicator protein product to confirm the presence of Salmonella spp. in 30-120 minutes. GlobalData’s report on Laboratory Corp of America Holdings gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Laboratory Corp of America Holdings, Molecular diagnosis biomarkers was a key innovation area identified from patents. Laboratory Corp of America Holdings's grant share as of January 2024 was 44%. Grant share is based on the ratio of number of grants to total number of patents.
Rapid detection of salmonella spp. in samples
A recently granted patent (Publication Number: US11873524B2) discloses a method for detecting Salmonella spp. in powdered infant formula samples. The method involves incubating the sample with a recombinant bacteriophage containing a genetic construct with an indicator gene and a promoter, followed by detecting the indicator protein product. Positive detection of the indicator protein product indicates the presence of Salmonella spp. in the sample.
Furthermore, the method claims the ability to detect as few as a single bacterium in a standard-sized sample for the food safety industry. It also includes variations such as using a cocktail composition of recombinant bacteriophages, an enrichment period before sample analysis, and a total time to results of less than 26 hours. Additionally, the patent highlights the importance of a high signal-to-background ratio for accurate detection, with a minimum ratio of 2.0 or 2.5 being specified in the claims.
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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.
