Materialise has filed a patent for a system that calibrates X-ray images. The system receives an X-ray image and a 3-D surface scan of the patient’s body. It then derives a measurement correction based on the surface scan, accounting for factors such as patient orientation and distances between the patient, detector plate, and X-ray source. The system determines a corrected measurement of the anatomical part based on this correction. GlobalData’s report on Materialise gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Materialise, Prosthetic cardiac valves was a key innovation area identified from patents. Materialise's grant share as of September 2023 was 41%. Grant share is based on the ratio of number of grants to total number of patents.

Calibrating x-ray images using 3-d surface scans

Source: United States Patent and Trademark Office (USPTO). Credit: Materialise NV

A recently filed patent (Publication Number: US20230263498A1) describes a system for calibrating X-ray images. The system includes at least one memory and at least one processor. The processor is configured to receive an X-ray image of an anatomical part of a patient and a 3-D surface scan of the corresponding portion of the patient. Based on the 3-D surface scan, the processor derives a measurement correction for the X-ray image. This correction takes into account factors such as the orientation of the patient with respect to the detector plate used to capture the X-ray image, the distance between the patient and the detector plate, and the distance between the patient and the X-ray source used to generate the image. The processor then determines a corrected measurement of the anatomical part based on the measurement correction and the measurement taken from the X-ray image.

To derive the measurement correction, the processor may derive the distances between the patient and the detector plate or the X-ray source based on the 3-D surface scan. It can also obtain the distance between the X-ray source and the detector plate and calculate a scaling factor using these distances. The processor can locate a region in the 3-D surface scan, such as an anatomical landmark, to calculate the distances. Alternatively, it can fit a statistical shape model (SSM) to the 3-D surface scan, resulting in a 3D model corresponding to the anatomical part, and calculate the distances based on a region of the 3D model.

The system can also determine the orientation of the patient based on the 3-D surface scan or the 3D model derived from the scan. Additionally, the processor can generate a patient-specific surgical design based on the corrected measurement. This design can be manufactured using additive manufacturing techniques.

In summary, the patent describes a system and method for calibrating X-ray images by using a 3-D surface scan of the patient. The system derives a measurement correction based on factors such as patient orientation and distances between the patient, the detector plate, and the X-ray source. This allows for more accurate measurements of anatomical parts in X-ray images and enables the generation of patient-specific surgical designs.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies