In Vitro Diagnostics (IVD) include reagents, instruments, and systems intended for use in the diagnosis of disease or other conditions, including the determination of the state of health, in order to treat or prevent disease. The reagents, instruments and systems are intended for use in the collection, preparation, and examination of specimens taken from the human body. The categories tracked under this market are Cardiac Disease, Hematological Disorders, Hormonal Disorders, Metabolic Disorder, Infectious Disease, IVD Analyzers and Reagents, Oncology and Reproductive Health Diagnostics. Next generation sequencing (NGS), or massively parallel sequencing, refers to high-throughput methods for DNA sequencing that are not Sanger-based, based on clonally amplified DNA templates or single DNA molecules rather than electrophoretic separation of chain-termination products produced in individual sequencing reactions. GlobalData uses proprietary data and analytics to provide a comprehensive report on the next generation sequencing market in the US. Buy the latest report here.

In 2022, GlobalData’s Market Model methodology determined that the leading player in the next generation sequencing market in the US was Agilent Technologies followed by Amoy Diagnostics, F. Hoffmann-La Roche, Illumina, New England Biolabs, Qiagen and Thermo Fisher Scientific.

Understanding market size can be crucial to evaluate opportunities and make informed decisions about market entry and exit. Medical device companies can identify attractive segments in respective markets as well as develop marketing strategies based on forecasts for those segments.

NGS technology has largely superseded Sanger sequencing in academic or genome research and is increasingly being applied in clinical practice. The technique is highly scalable and typically involves fragmenting the genome and then randomly sampling for and sequencing these fragments. NGS can be performed on formalin-fixed and paraffin-embedded (FFPE) and freshly collected tissue specimens and on fine-needle aspiration samples and small biopsy specimens. NGS encompasses a number of different sequencing platforms; whole-genome sequencing, exome sequencing, transcriptome sequencing (mRNA sequencing), and targeted sequencing of multigene panels, all of which simultaneously sequence millions of DNA fragments and later reply on bioinformatics analysis to map these reads to a human reference genome. In this model, GlobalData has considered pyrosequencing reagents to be NGS tests.

The next generation sequencing market in the US can expand or contract due to a variety of reasons including population demographics, disease incidence and prevalence, macroeconomic issues, and geopolitical considerations. Disruption to a market could be caused by a sudden, unexpected change in these factors, but it could also be driven by changes in clinical practice, leading to a change in diagnosis or treatment of patients, as part of a process to generally improve medical practice.

For the latest analysis of the market size next generation sequencing in the US, buy the report here.

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Medical Intelligence Center Market Models are the gold standard of medical device market valuation, company share estimation and market trend forecasting. GlobalData uses a patient-based forecast model or installed base methodology to determine the market size for therapeutic indications and capital equipment expenditures. Estimates are based on a number of sources, including primary research—KOL and industry contact interviews—and secondary research, such as company reports, press releases, published articles, proprietary databases, and general news media.