Repligen has been granted a patent for a fluid management system that connects various subsystems without the need for reinforced tubing. The system uses unreinforced conduit segments encapsulated with rigid members, allowing for disposable conduit and reusable encapsulating members. The system includes two-part valve bodies and jackets that can be joined at different points within the overall flow system. GlobalData’s report on Repligen gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Repligen, rtRNA virus peptides was a key innovation area identified from patents. Repligen's grant share as of September 2023 was 43%. Grant share is based on the ratio of number of grants to total number of patents.

Fluid management system with encapsulated unreinforced polymer conduit

Source: United States Patent and Trademark Office (USPTO). Credit: Repligen Corp

A recently granted patent (Publication Number: US11754191B2) describes a fluid management system for handling pressurized fluid in a fluidized process, particularly in pharmaceutical or biological production processes. The system includes an unreinforced polymer conduit with a cross-shaped lumen to carry the pressurized fluid. The conduit is encapsulated and surrounded by a two-part jacket, which forms a cross-shaped assembly and a passageway that matches the exterior shape of the conduit. The jacket provides resistance to expansion of the conduit and is held together with a pair of fasteners.

The first and second halves of the jacket are further held together with a pair of projections that extend from the second half and fit into corresponding recesses in the first half. This creates a friction fit between the projections and the recess, ensuring a secure closure of the jacket. Flanges are also disposed at the ends of the jacket, and the unreinforced polymer conduit has respective flanges that fit within the end flanges of the jacket.

The pair of fasteners in the system consist of threaded latches and knobs. The threaded latches are pivotable and rotatable into notches located in the second half of the jacket. By loosening the fasteners, the two-part jacket can be opened to replace the unreinforced polymer conduit with another segment of the same material.

The patent also mentions the use of a sensor housing in the jacket, which can receive a sensor for monitoring the fluid within the system.

Overall, this fluid management system provides a secure and efficient way to handle pressurized fluid in pharmaceutical or biological production processes. The use of an unreinforced polymer conduit and a two-part jacket with fasteners allows for easy replacement of the conduit while maintaining the integrity of the system. The inclusion of a sensor housing further enhances the functionality of the system by enabling fluid monitoring.

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.