Repligen has been granted a patent for a valve assembly with a multidirectional flow path, allowing selective fluid direction through flexible tubing branches. The method involves creating a flexible conduit with minimal hold-up volumes using overmolded connectors. This innovation can be integrated into manufacturing processes. GlobalData’s report on Repligen gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Repligen, rtRNA virus peptides was a key innovation area identified from patents. Repligen's grant share as of February 2024 was 54%. Grant share is based on the ratio of number of grants to total number of patents.

Method of making a flexible conduit with loop portion

Source: United States Patent and Trademark Office (USPTO). Credit: Repligen Corp

A recently granted patent (Publication Number: US11898645B2) discloses a method for producing a flexible conduit with a loop portion. The method involves using a double cross-shaped tubing section, along with two Y or TEE tubing sections, connected through overmolded connectors. These connectors ensure the bonding of the three separate tubing pieces, minimizing hold-up volumes within the conduit when closed by valves positioned around the intersections. The spacing between the sections allows for a flexible tubing portion, enhancing the efficiency of the conduit.

Furthermore, the patent details the use of mandrels during the molding process to form the overmolded connectors, which are designed as bubble connectors or made from silicone. By positioning the mandrels inside the tubing sections and the double cross-shaped section, the connectors are formed before the mandrels are removed, ensuring a secure and efficient connection. This innovative method aims to improve the functionality and performance of flexible conduits, particularly in applications where minimizing hold-up volumes is crucial for operational efficiency.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.