SurModics has patented a lubricious medical device coating with layers of polyvinylpyrrolidone and acrylamide-containing copolymers cross-linked with photoreactive groups. The coating includes sodium bis(4-benzoylphenyl) phosphate. GlobalData’s report on SurModics gives a 360-degree view of the company including its patenting strategy. Buy the report here.
According to GlobalData’s company profile on SurModics, Bioresorbable stent coating was a key innovation area identified from patents. SurModics's grant share as of January 2024 was 49%. Grant share is based on the ratio of number of grants to total number of patents.
Lubricious medical device coating with polyvinylpyrrolidone and acrylamide copolymer
A recently granted patent (Publication Number: US11872325B2) discloses a medical device with a unique composition aimed at improving performance and safety. The device includes a substrate with a first layer comprising polyvinylpyrrolidone derivatized with a photoreactive group, along with specific acrylamide-containing copolymers and sodium bis(4-benzoylphenyl) phosphate (BPP). The coating on the device is designed to release less than 10,000 particles larger than 10 microns when exposed to water, ensuring minimal particle release during use.
Furthermore, the patent details specific ratios of ingredients in the first layer, such as the polyvinylpyrrolidone derivatized with a photoreactive group to BPP ratio, which contributes to the coating's lubricity and durability. The coating is designed to exhibit a lubricity between 0 and 30 grams of force when wetted, with consistent performance over multiple testing cycles. Additionally, the thickness of the first layer is specified to be between 100 and 3000 nm when dry. The patent also mentions the use of benzophenone as the photoreactive group and highlights the application of this technology in balloon catheters and other medical devices with catheter shaft substrates.
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