Talis Biomedical has been granted a patent for a magnetic mixing apparatus that efficiently mixes samples in a mixing chamber using a stir bar. The method involves lysing cells in a fluid sample by rotating the stir bar magnetically coupled between driving and driven magnets. GlobalData’s report on Talis Biomedical gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Talis Biomedical, Microfluidics automation was a key innovation area identified from patents. Talis Biomedical's grant share as of May 2024 was 15%. Grant share is based on the ratio of number of grants to total number of patents.
Magnetic mixing apparatus for lysing cells in fluid samples
A recently granted patent (Publication Number: US11998883B2) outlines a method for lysing cells within a fluid sample using a mixing assembly. The process involves loading the sample into a mixing chamber, applying pneumatic pressure to advance the sample, rotating a drive magnet system to mix the sample with a stir bar, producing a lysed sample, and filtering it through a sample exit channel. Additional steps include closing inlet and outlet channels during lysing, introducing a lysis buffer, and using chemical lysing agents. The method also includes detecting decoupling of the stir bar and adjusting the process accordingly.
Furthermore, the patent describes a method for mixing a fluid sample containing cells within a mixing chamber of a mixing assembly. This process involves loading the sample, applying pneumatic pressure, rotating magnetic systems to mix the sample with a stir bar, and advancing the sample through a filter channel. Additional steps include loading a lysis buffer, mixing the sample with the buffer, and specifying dimensions for the mixing chamber and stir bar. The gap between the magnetic systems, the volume of the mixing chamber, and the stir bar volume are also defined within the patent. These methods offer a detailed and innovative approach to lysing and mixing cells within fluid samples, providing a potential solution for various scientific and medical applications.
To know more about GlobalData’s detailed insights on Talis Biomedical, buy the report here.
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