West Pharmaceutical Services has been granted a patent for a container designed to store pharmaceutical compositions. The container includes a body portion made of elastomeric material and an inner lining made of thermoplastic material. The inner lining acts as a barrier between the elastomeric material and the pharmaceutical composition, protecting it. The container also features multiple internal chambers and a channel connecting them. Methods for storing and manufacturing the container are also described. GlobalData’s report on West Pharmaceutical Services gives a 360-degree view of the company including its patenting strategy. Buy the report here.
According to GlobalData’s company profile on West Pharmaceutical Services, Wearable drug delivery devices was a key innovation area identified from patents. West Pharmaceutical Services's grant share as of September 2023 was 51%. Grant share is based on the ratio of number of grants to total number of patents.
Container with elastomeric body and thermoplastic inner lining
A recently granted patent (Publication Number: US11771623B2) describes a container for storing pharmaceutical compositions. The container includes a body portion made of elastomeric material and an inner lining made of thermoplastic material. The inner lining covers at least a portion of the inner surface of the body portion and acts as a barrier between the elastomeric material and the pharmaceutical compositions. The container has multiple internal chambers for storing the pharmaceutical compositions, and these chambers are bounded by the inner surface of the body portion. Additionally, there is a channel that connects two or more of the internal chambers.
The elastomeric material used in the container can be a thermoelastic elastomer or a thermoset elastomer. It is specified that the elastomeric material should be of pharmaceutical grade. The inner lining is made up of multiple sheets of thermoplastic material, forming a laminate structure. The channel in the container is sealed by a breakable seal, which prevents fluid communication between the connected internal chambers until the seal is broken.
The container also includes an access port that provides fluid communication with at least one of the internal chambers. The access port extends from the body portion of the container and may have a sealed end, which can be resealable. The access port's internal surface is covered by the inner lining. In some embodiments, the access port is sealed with an elastomeric stopper.
The container may further include a valve in the channel, which is a one-way valve allowing fluid flow in one direction but preventing flow in the opposite direction. This valve helps control the movement of the pharmaceutical compositions within the container.
The patent also describes methods for filling the internal chambers of the container with pharmaceutical compositions. The method involves filling different internal chambers with the same or different compositions and connecting them through the channel. The channel has a seal that prevents fluid communication between the chambers until the seal is broken.
The manufacturing method for the container includes forming the body portion with the elastomeric material and the inner lining. A bladder is formed from the thermoplastic layer of the inner lining material. The body portion is then formed around the bladder and cured. An opening is left in the inner lining by leaving a section of the body portion's edge unsealed. Additionally, a breakable seal is formed in the channel to prevent fluid communication between the internal chambers until the seal is broken.
Overall, this patent presents a container design and manufacturing method that provides a barrier between the elastomeric material and pharmaceutical compositions, allowing for safe storage and controlled access to multiple internal chambers.