The Aventa FusionPlus test helps identify gene fusions, translocations and rearrangements across 361 genes from FFPE tumour tissue. Credit: Arek Socha from Pixabay.

Aventa Genomics has launched its next-generation sequencing (NGS) test, Aventa FusionPlus, to identify gene fusions and translocations, along with rearrangements across 361 genes from formalin-fixed, paraffin-embedded (FFPE) solid tumour tissue.

The test incorporates 3D genomics technology, leveraging the preservation of spatial proximity of rearranged and fused genes for a 100–1,000-fold signal amplification and detection of new breakpoints and fusion partners.

Go deeper with GlobalData

Premium Insights

The gold standard of business intelligence.

Find out more

Aventa Genomics executive director Chris Roberts said: “In previously characterised tumour specimens from patients with no known actionable driver, the Aventa FusionPlus test detected potentially actionable variants in half of the cases.

“The increase in diagnostic yield from detecting actionable biomarkers FISH and RNA sequencing miss, we believe, will provide more treatment options and will facilitate improved patient management.”

The test helps detect biomarkers that are missed by conventional testing methods such as fluorescent in situ hybridisation and RNA sequencing, apart from actionable biomarkers.

See Also:

Furthermore, it leverages analysis and reporting platforms to comprehensively assess the tumour.

How well do you really know your competitors?

Access the most comprehensive Company Profiles on the market, powered by GlobalData. Save hours of research. Gain competitive edge.

Company Profile – free sample

Thank you!

Your download email will arrive shortly

Not ready to buy yet? Download a free sample

We are confident about the unique quality of our Company Profiles. However, we want you to make the most beneficial decision for your business, so we offer a free sample that you can download by submitting the below form

By GlobalData
Visit our Privacy Policy for more information about our services, how we may use, process and share your personal data, including information of your rights in respect of your personal data and how you can unsubscribe from future marketing communications. Our services are intended for corporate subscribers and you warrant that the email address submitted is your corporate email address.

The company uses its Clinical Laboratory Improvement Amendments-certified laboratory in Orlando, Florida, to perform testing services.

Aventa Genomics medical director Anthony Magliocco said: “The Aventa FusionPlus test is unique in the market and we believe it offers physicians a powerful new tool to reveal druggable targets and resolve diagnostic dilemmas.

“We are happy to make this innovative, clinically impactful, precision laboratory-developed diagnostic test available to treating physicians for the benefit of their patients.”

The company is a joint venture between Protean BioDiagnostics and Arima Genomics and offers 3D Genomics tools for identifying druggable targets.