A clinical validation study carried out by Cleveland Clinic has shown that using a new blood test called IsoPSA could have avoided 47% of biopsies performed to identify prostate cancer.

Previous studies also revealed similar results (45.1%), indicating the use of IsoPSA in lowering the chances of over-detection and over-treatment of non-lethal prostate cancer.

Go deeper with GlobalData

Premium Insights

The gold standard of business intelligence.

Find out more

Related Company Profiles

View all

Named Prospective Validation of the IsoPSA Assay for Detection of High Grade Prostate Cancer, the latest study compared the accuracy of IsoPSA with standard prostate-specific antigen (PSA) at predicting the overall risk of the cancer.

“The capability of the test to identify high-grade cancer is expected to minimise unnecessary biopsies in patients who are at low risk of the disease.”

The multi-centre study was intended to validate the results from early studies where the new blood test was able to differentiate between high-grade and low-grade/benign cancer.

The capability of the test to identify high-grade cancer is expected to minimise unnecessary biopsies in patients who are at low risk of the disease.

Cleveland Clinic Glickman Urological & Kidney Institute chair Eric Klein said: “To be clinically useful, a biomarker must be both tissue-specific and cancer-specific.

How well do you really know your competitors?

Access the most comprehensive Company Profiles on the market, powered by GlobalData. Save hours of research. Gain competitive edge.

Company Profile – free sample

Thank you!

Your download email will arrive shortly

Not ready to buy yet? Download a free sample

We are confident about the unique quality of our Company Profiles. However, we want you to make the most beneficial decision for your business, so we offer a free sample that you can download by submitting the below form

By GlobalData
Visit our Privacy Policy for more information about our services, how we may use, process and share your personal data, including information of your rights in respect of your personal data and how you can unsubscribe from future marketing communications. Our services are intended for corporate subscribers and you warrant that the email address submitted is your corporate email address.

“While PSA is prostate-specific, it is not specific for prostate cancer, leading to diagnostic inaccuracy and too many unneeded biopsies.

“IsoPSA fulfils both the tissue- and cancer-specificity needed for a useful biomarker, and this validation study shows that it can more accurately detect high-grade cancer and reduce the rate of unneeded biopsies in patients at low risk of this disease.”

Developed by Cleveland Diagnostics, IsoPSA is a structure-based assay designed to analyse the structural changes of complex PSA.

Last year, Cleveland Diagnostics signed an exclusive licensing agreement with Genomic Health for the development and commercialisation of the test.