Switzerland-based bioinformatics solutions provider Genedata has created new algorithms to aid in the early detection of breast cancer and certain ovarian cancers.

Under the European Union (EU) funded EpiFemCare, Genedata scientists used the firm’s software platform called Genedata Profiler to process and analyse huge volumes of data obtained from patient blood samples for the detection of tumour DNA markers.

While tumour DNA markers aid in the identification of cancer cells even in initial stages, they become extremely diluted in serum samples and could not be detected easily.

The new algorithms are designed to address concerns with existing methods by detecting and quantifying even little amounts of tumour DNA with high sensitivity and specificity.

When used in the EpiFemCare project, the algorithms have led to the discovery of a new serum DNA methylation marker called EFC#93 that has the potential to diagnose breast cancer around one year before existing methods.

“They expect that these findings could pave way for the personalised treatment of breast or ovarian cancer patients.”

The researchers further found that DNA methylation patterns in a specific panel of markers could identify select ovarian cancers around two years prior to diagnosis.

How well do you really know your competitors?

Access the most comprehensive Company Profiles on the market, powered by GlobalData. Save hours of research. Gain competitive edge.

Company Profile – free sample

Thank you!

Your download email will arrive shortly

Not ready to buy yet? Download a free sample

We are confident about the unique quality of our Company Profiles. However, we want you to make the most beneficial decision for your business, so we offer a free sample that you can download by submitting the below form

By GlobalData
Visit our Privacy Policy for more information about our services, how we may use, process and share your personal data, including information of your rights in respect of your personal data and how you can unsubscribe from future marketing communications. Our services are intended for corporate subscribers and you warrant that the email address submitted is your corporate email address.

They expect that these findings could pave way for the personalised treatment of breast or ovarian cancer patients.

Study coordinator professor Martin Widschwendter said: “For the first time, our study provides evidence that serum DNA methylation markers such as EFC#93 provide a highly specific indicator that could diagnose fatal breast cancers up to one year in advance of current diagnosis.

“This may enable individualised treatment, which could even begin in the absence of radiological evidence in the breast.”