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March 26, 2018

Italian researchers develop breast cancer imaging device

Researchers at Politecnico di Milano, Italy have developed an optical mammography (OM) instrument that uses harmless red or infrared light for diagnostic imaging or monitoring of breast cancer patients.

Researchers at Politecnico di Milano, Italy have developed an optical mammography (OM) instrument that uses harmless red or infrared light for diagnostic imaging or monitoring of breast cancer patients.

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The device is meant to be used in combination with X-rays to avoid high ionising radiation in people who require repeated imaging. It has been developed under the Smart Optical and Ultrasound Diagnostics of Breast Cancer (SOLUS) project.

Instead of two photomultiplier tubes (PMTs) seen in current X-ray mammography devices, the new instrument contains an eight-channel probe with silicon photomultipliers (SiPMs) and a multichannel time-to-digital converter.

“The device is meant to be used in combination with X-rays to avoid high ionising radiation in people who require repeated imaging.”

The latest additions are intended to avoid a time-consuming pre-scan commonly performed to not damage the PMTs, and are said to be responsible for the increased sensitivity and decreased expenses.

Optical imaging methods can be used to analyse tissue composition, including measurement of blood volume, oxygenation, lipid, water and collagen content in a suspected area identified using conventional X-ray imaging technique.

However, OM imaging lacks in the spatial resolution area and its combination with other imaging approaches is expected to address this challenge.

OM instruments also require the exertion of gentle pressure or some need none at all as they work by employing rings of light sources and detectors. OM is considered best applicable in pre-surgical chemotherapy.

Research co-author Edoardo Ferocino said: “This technique is able to provide information on the outcome of chemotherapy just weeks after beginning treatment, or possibly even sooner.”

Ferocino and his team intend to further study the applications of OM in monitoring and predicting chemotherapy outcomes.

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Medical Device Industry Landscape In Asia-Pacific

GlobalData's APAC Medical Devices Industry Landscape – 2022 free study breaks down the APAC medical devices market by segment and region and includes insights on local and global competitors, pipeline product developments, clinical trials studies, and significant deals in the industry. The APAC medical device industry witnessed significant developments, launches, implementations, and adoption of new medical device technologies in the past decade, however the high cost of devices, regulatory hurdles, reimbursement pressure, and healthcare budget constraints have challenged market expansion across various territories and segments. APAC is the fastest growing regional market for medical device clinical trials, with China and Japan emerging as major clinical trial hotspots. The growth in medical device clinical trials in the APAC region is attributed to an increase in research partnerships between biopharma companies and clinical research organizations (CROs). This report also provides an in-depth analysis of the medical device market's opportunities and challenges, the influence of COVID-19 on the market, and government activities aimed to develop the APAC medical device market.
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