US-based wound care solutions provider Acelity has reported positive results from a clinical study of its PREVENA Incision Management System in obese patients undergoing caesarean delivery with closed incision negative pressure therapy (ciNPT).

Introduced in 2010, PREVENA is a disposable negative pressure system developed for managing closed surgical incisions.

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The system covers and protects the surgical incision from external contamination, while its negative pressure removes fluid and infectious material from the incision.

When compared to standard-of-care (SOC) dressing, the results showed a decrease in post-surgical wound complications, narcotic use, post-operative pain, and surgical site occurrences (SSOs).

With 82 patients, the single-centre, randomised, controlled study compared SSOs such as unanticipated local inflammatory response, prolonged drainage, fluid collection, dehiscence, and surgical site infection in subjects treated with ciNPT using the PREVENA system and those given SOC.

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"This compelling new data suggests that negative pressure wound therapy may be used to reduce post-operative pain in surgical patients."

Acelity chief medical officer Ron Silverman said: “This compelling new data suggests that negative pressure wound therapy may be used to reduce post-operative pain in surgical patients.

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“By examining patients at greater risk of complications and increased costs in this study, we can now point to definitive, exciting data that shows PREVENA Therapy improves the patient experience by reducing pain.

“This study adds to the growing body of evidence that demonstrates a potential reduction in post-operative wound complications in a variety of surgical incisions.”

With ciNPT, there was 5.1% of SSOs and incisional pain at rest was 43.5%. There was also 54.3% of incisional pressure and total opioid use decreased by 30%, demonstrating a significant drop compared to SOC.