Data scientists from UK artificial intelligence (AI) company PrecisionLife have identified 59 repurposing drug candidates that could potentially treat patients who develop sepsis while suffering from severe Covid-19.

The study, released today on open-access repository bioRxiv, sought to identify genetic risk factors for sepsis in the context of Covid-19. These insights were then used to identify existing drugs that might be used to treat life-threatening late-stage disease.

Sepsis is observed in around 60% of severe Covid-19 patients, the company said.

The PrecisionLife team has identified mutations in 70 sepsis risk genes, 61% of which were also present specifically in severe Covid-19 patients. Of these genes, 13 are known to be druggable, with 59 compounds and drugs known to be active against these 13 targets.

These compounds could now form the basis for future drug trials and repurposing projects.

How well do you really know your competitors?

Access the most comprehensive Company Profiles on the market, powered by GlobalData. Save hours of research. Gain competitive edge.

Company Profile – free sample

Thank you!

Your download email will arrive shortly

Not ready to buy yet? Download a free sample

We are confident about the unique quality of our Company Profiles. However, we want you to make the most beneficial decision for your business, so we offer a free sample that you can download by submitting the below form

By GlobalData
Visit our Privacy Policy for more information about our services, how we may use, process and share your personal data, including information of your rights in respect of your personal data and how you can unsubscribe from future marketing communications. Our services are intended for corporate subscribers and you warrant that the email address submitted is your corporate email address.