ClearPoint Neuro. has filed a patent for an MRI-compatible cannula designed for delivering substances to the brain. The system includes a delivery cannula with a flat end face, a circuit for MRI scanner communication, and a display for real-time visualization of substance dispersion in the brain. GlobalData’s report on ClearPoint Neuro gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on ClearPoint Neuro, Transcranial ultrasound was a key innovation area identified from patents. ClearPoint Neuro's grant share as of January 2024 was 46%. Grant share is based on the ratio of number of grants to total number of patents.

Mri-compatible cannula for delivering substance to brain with real-time visualization

Source: United States Patent and Trademark Office (USPTO). Credit: ClearPoint Neuro Inc

A newly filed patent (Publication Number: US20240017005A1) describes a surgical system designed to deliver substances to the brain of a patient with precision and real-time monitoring capabilities. The system includes an MRI-compatible delivery cannula with a flat end face, a circuit that communicates with an MRI scanner, and at least one display for visualizing the dispersion and infusion pattern of the substance in the patient's brain. The system allows for the delivery of various substances such as chemotherapeutic agents, stem cells, gene therapy, and antigens, with adjustable operational parameters for fine-tuning the treatment structure and volume of tissue in the brain.

The patent also outlines a method for delivering substances to the brain in an MRI-guided surgical procedure. This involves delivering the substance using the MRI-compatible delivery cannula while the patient is in the MRI scanner, obtaining MRI image data, and generating real-time visualizations to aid in the surgical procedure. The method includes adjusting the substance flow based on the displayed visualizations, mounting the cannula to an MRI-compatible guide frame for precise positioning, and extending or retracting the transfer tube inside the brain at a target neurological site. Overall, the system and method described in the patent aim to enhance the accuracy and effectiveness of delivering substances to the brain while providing real-time monitoring capabilities through MRI imaging.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies