Getinge‘s patented method enhances fluorescence imaging by optimizing information use through a calibration protocol and a “rolling shutter” camera mode. It involves sequential signal recording from photosensor groups, applying correction factors, and utilizing controlled light sources to improve image reconstruction of regions of interest. GlobalData’s report on Getinge gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Getinge, Automatic disinfection robots was a key innovation area identified from patents. Getinge's grant share as of June 2024 was 60%. Grant share is based on the ratio of number of grants to total number of patents.

Fluorescence imaging method with optimized calibration and synchronization

Source: United States Patent and Trademark Office (USPTO). Credit: Getinge AB

The patent US12041364B2 outlines an innovative imaging method that utilizes a matrix of photosensors to capture and process images of a region-of-interest under varying light conditions. The method involves recording electrical signals that represent pixel brightness, generated by two groups of photosensors. A closed-loop control system sequentially records signals from these groups while managing the activation of a first light source in conjunction with a second light source. The process includes subtracting values from recorded signals during different time periods and applying a correction factor derived from calibration measurements. This calibration involves capturing images under continuous and periodic illumination from a calibration light source, ensuring accurate image reconstruction.

Additionally, the patent describes an apparatus designed to implement this imaging method. The apparatus features a matrix of photosensors sensitive to a specific wavelength range, a pulsed light source for exciting fluorophores, and a synchronizer to coordinate the light source's operation with the photosensor's signal integration. The processor within the apparatus is responsible for calculating the difference between recorded signal values and applying the necessary correction factors. The design allows for precise control over the imaging process, enhancing the quality and accuracy of the captured images. The patent also includes provisions for executing the method via a non-transitory computer-readable medium, indicating its potential for integration into various imaging technologies.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.