Illumina. has been granted a patent for substituted dyes featuring bis-boron fused heterocycles, which serve as fluorescent labels. These compounds are specifically designed for use in nucleic acid sequencing applications, enhancing the detection of nucleotides. GlobalData’s report on Illumina gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Illumina, Microfluidics automation was a key innovation area identified from patents. Illumina's grant share as of June 2024 was 42%. Grant share is based on the ratio of number of grants to total number of patents.
Fluorescent dyes for nucleic acid sequencing applications
The patent US12043637B2 outlines a series of claims related to novel compounds, specifically those represented by a defined chemical structure (Formula I). The claims detail various structural modifications and substitutions for these compounds, including specific groups such as halo, cyano, carboxyl, and alkyl groups. The patent also describes the potential for these compounds to be incorporated into nucleotides, with particular emphasis on their attachment via carboxyl groups. Additionally, the claims extend to oligonucleotides or polynucleotides that incorporate these labeled nucleotides, highlighting their application in hybridization processes with target polynucleotides immobilized on solid supports.
Furthermore, the patent includes claims for kits that contain multiple types of labeled nucleotides, which may be used in conjunction with DNA polymerase and buffer compositions. A method for determining the sequences of target polynucleotides is also described, involving the use of sequencing primers and the incorporation of the labeled nucleotides during DNA polymerase-mediated primer extension. This method aims to facilitate the identification of nucleotide sequences through fluorescent measurements of the extended polynucleotides, showcasing the practical applications of the compounds and kits outlined in the patent.
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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.
