NanoString Technologies has been granted a patent for chemical compositions, kits, and methods for assays. The patent includes a probe with a target binding domain linked to a barcode domain, allowing for identification of target nucleic acids. GlobalData’s report on NanoString Technologies gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on NanoString Technologies, Personalized medicine biomarkers was a key innovation area identified from patents. NanoString Technologies's grant share as of January 2024 was 36%. Grant share is based on the ratio of number of grants to total number of patents.
Probes for identifying target nucleic acids in assays
A recently granted patent (Publication Number: US11821026B2) discloses a probe design comprising a target binding domain linked to a barcode domain. The target binding domain consists of at least eight nucleotides, with six nucleotides capable of identifying a target nucleic acid and two nucleotides that do not. The barcode domain includes attachment positions with nucleic acid sequences determining the identity of the bound target nucleic acid. The barcode domain is specified to contain single-stranded DNA, with each attachment position having one attachment region.
Furthermore, the patent claims detail the arrangement of nucleotides in the target binding domain, with specific sequences complementary to the target nucleic acid. The probes may also include complementary nucleic acid molecules with detectable labels like fluorescent labels. The patent covers a population of probes with varying nucleotide lengths in the target binding domain, ranging from eight to ten nucleotides, all capable of identifying the target nucleic acid molecule. This innovative probe design offers a versatile and efficient tool for identifying and binding target nucleic acids, with potential applications in various fields such as molecular biology and diagnostics.
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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.
