Nevro has filed a patent for a system and methods to detect impedance changes and adjust electrical therapy accordingly. The method involves applying a paresthesia-less electrical signal to a patient and monitoring the impedance of the electrical circuit to detect faults. GlobalData’s report on Nevro gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Nevro, Neuromodulation implants was a key innovation area identified from patents. Nevro's grant share as of September 2023 was 62%. Grant share is based on the ratio of number of grants to total number of patents.

System and methods for adjusting electrical therapy based on impedance changes

Source: United States Patent and Trademark Office (USPTO). Credit: Nevro Corp

A recently filed patent (Publication Number: US20230293889A1) describes a method for controlling a patient therapy device. The method involves applying a therapeutic electrical signal to a target neural population in a patient using an implantable portion of a patient modulation system. The electrical signal is designed to provide pain relief without causing paresthesia, a tingling or prickling sensation. The method also includes detecting a change in the impedance of the electrical circuit that delivers the electrical signal, without the patient sensing a corresponding change in therapy. Once the change in impedance is detected, a notification is provided to prompt the patient and/or a practitioner to correct or compensate for the change.

The notification is designed to be provided prior to the patient experiencing a change in therapy resulting from the change in impedance. It can elicit a corrective or compensatory response, which may involve changing the active contact applying the electrical signal, changing the number of active contacts used, increasing the strength of the electrical signal, or updating the values of the signal delivery parameters. The notification is generated by the implantable portion of the patient modulation system and transmitted to an external device.

Another aspect of the patent involves monitoring the impedance of the electrical circuit on a pre-set periodic basis. This allows for the detection of any changes in impedance that may indicate a fault before or without the patient sensing a change in therapy resulting from the fault. In response to detecting the change in impedance, a notification is provided to prompt the patient and/or practitioner to correct or compensate for the fault. The corrective or compensatory response can involve the same actions as mentioned earlier.

The patent also describes a patient therapy system that includes a patient-implantable portion with a signal generator and a signal delivery device. The system further includes an impedance detector and a processor. The impedance detector is used to monitor the impedance of the electrical circuit, and the processor is programmed to receive indications of changes in impedance and generate notifications to prompt corrective or compensatory actions.

Overall, this patent presents a method and system for controlling a patient therapy device that ensures the delivery of a therapeutic electrical signal without causing paresthesia. It also provides a mechanism for detecting changes in impedance and notifying the patient and/or practitioner to take corrective actions. This technology has the potential to improve the effectiveness and safety of patient therapy devices.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies