PerkinElmer has been granted a patent for compositions and methods involving anti-TSPAN33 agents, such as monoclonal antibodies and antibody fragments, that bind to Tetraspanin 33 (TSPAN33) under various conditions. The agents consist of specific immunoglobulin heavy and light chain variable domains with complementarity determining regions. GlobalData’s report on PerkinElmer gives a 360-degree view of the company including its patenting strategy. Buy the report here.
According to GlobalData’s company profile on PerkinElmer, Laboratory automation robots was a key innovation area identified from patents. PerkinElmer's grant share as of May 2024 was 50%. Grant share is based on the ratio of number of grants to total number of patents.
Patent granted for anti-tspan33 agents using monoclonal antibodies
The granted patent (Publication Number: US12006363B2) discloses an anti-TSPAN33 agent designed to bind Tetraspanin 33 (TSPAN33) under laboratory or physiological conditions. The agent consists of at least one immunoglobulin heavy chain variable domain and at least one immunoglobulin light chain variable domain, each containing specific complementarity determining regions (CDRs) with defined amino acid sequences. The agent can be further characterized by its similarity to specific amino acid sequences, its conjugation to detectable markers or labels, and its non-diffusive immobilization on a solid support.
Moreover, the patent covers the isolated nucleic acid molecules encoding the immunoglobulin heavy chain variable domain or the immunoglobulin light chain variable domain of the anti-TSPAN33 agent, as well as a recombinant expression vector for their production. Additionally, the patent describes methods for detecting TSPAN33 by utilizing the anti-TSPAN33 agent to form TSPAN33:anti-TSPAN33 complexes in samples containing TSPAN33. Furthermore, the patent includes a method for treating or preventing diseases or disorders associated with abnormal levels of TSPAN33 by administering the anti-TSPAN33 agent to individuals requiring such treatment, thereby effectively managing the condition.
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