Sartorius has been granted a patent for a perfusion filtration module or bioreactor that uses a plurality of hollow fiber filter membranes to reduce fouling. The module allows the filter membranes to be held in a splayed configuration, increasing the distance between them and improving filtration efficiency. The patent also includes specific details about the shape and degree of splay of the membranes. The module is housed in a fixed position relative to the housing. GlobalData’s report on Sartorius gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Sartorius, Hydrogen fuel cells was a key innovation area identified from patents. Sartorius's grant share as of September 2023 was 55%. Grant share is based on the ratio of number of grants to total number of patents.

Patent granted for a perfusion filtration module with splayed membranes

Source: United States Patent and Trademark Office (USPTO). Credit: Sartorius AG

A recently granted patent (Publication Number: US11772048B2) describes a perfusion filtration module and a membrane bioreactor system incorporating this module. The module consists of a plurality of hollow fiber filter membranes, each with a potted first end and a second end that can be either potted or mounted. The module also includes a constraint that holds the filter membranes in a splayed configuration, where they spread out from each other to increase the interstitial distance between them. The splayed configuration has a degree of splay between 2 and 7. The module is housed in a housing, and the potted or mounted ends of the filter membranes are fixed relative to the housing.

The patent also mentions the inclusion of a protective enclosure for the perfusion filtration module, which can be made of metal or plastic and may include woven or non-woven fabrics, plastics, or metals. The first and second shapes of the surfaces from which the filter membranes emerge are described as convex, and the first and second ends of the filter membranes are mounted or potted at angles approximately normal to these surfaces.

In addition to the filtration module, the patent also describes a membrane bioreactor system that incorporates this module. The system includes a bioreactor and the perfusion filtration module positioned within it. The system may also include an agitation system, such as a stirring system, and a collection vessel to collect the permeate extracted from the bioreactor by the filtration module.

Overall, this patent describes a perfusion filtration module and a membrane bioreactor system that utilize a splayed configuration of hollow fiber filter membranes to increase the interstitial distance between them. This configuration, along with the fixed ends and housing, allows for efficient filtration. The inclusion of a protective enclosure and additional components like an agitation system and collection vessel further enhance the functionality of the system.

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.