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Medical Device Sterilisation

13, chemin du Pontet,
69 380 Civrieux d’Azergues ,

13, chemin du Pontet,
69 380 Civrieux d’Azergues ,

The French company Ionisos is one of the first companies in the world to have put ionising rays to good use for the sterilisation of medical devices. Originally known as Conservatome (from 1958 to 1993), Ionisos came into being in 1993 following a merger between Conservatome and Amphytrion. Ionisos now offers cold sterilisation for a range of applications, including:

  • Disposable medical supplies
  • Items of packaging: bottles, capsules, stoppers
  • Pharmaceutical industry raw materials or finished products

After different acquisitions, in 2004 further progress in their expansion policy allowed Ionisos to take over COFRAR, a leader company in engineering and realisation of e-beam sterilisation.

In 2007 Ionisos was also integrated with Ionmed, a well established e-beam treatment supplier located near Madrid (Spain).

Ionisos is a major partner in sterilisation in Europe. The company has nine plants, including six in France, one in Estonia, one in Germany and one in Spain. These include:

  • Four plants in gamma rays: Dagneux (near Lyon, France), Sablé (near Le Mans, France), Pouzauges (near Nantes, France), Saue vald (Estonia)
  • Five plants in E-beam: Chaumesnil, (near Troyes, France), Ionisos Iberica in Tarancon (near Madrid, Spain), Monza and Biassono (Italy), and Bautzen (Germany)
  • Four plants using EO: Sterylene in Gien (near Orleans, France), Civrieux d’Azergues (France), Monza (Italy) and Reggiolo (near Milan, Italy)

The Cobalt 60 gamma ray

The gamma ray from Cobalt 60 is safe, reproducible and immediately useable with a high penetrating power treatment.

The beta ray from an e-beam generator

The beta ray produced via an e-beam generator provides the same features, except the penetrating power, less important than in gamma rays. The beta ray, however, is more adaptable within the changing process.

EO sterilisation

Ionisos also offers EO sterilisation using EO gas. The EO sterilisation method allows a more flexible, reliable and efficient process.

Quality sterilisation services

Years of experience and geographic implantation allow Ionisos to work with all major companies involved in medical and pharmaceutical devices. Ionisos customers are present in a vast range of businesses requiring medical sterilisation: medical devices, laboratory material, aseptic production and packaging.

Ionisos is developing a partnership with its customers based on a quality assurance contract enabling it to meet the stringent requirements of this business sector.

All Ionisos plants are ISO 9001, ISO 13485, ISO 11137, ISO 14001 approved. Ionisos is steadily audited by the GMed as it continues to work with many international companies.

More than ever, Ionisos is offering reliable, high-quality solutions to sterilisation projects for all kind of products, with all countries.

Ionisos Facility List

Ionisos is your partner in sterilisation by ionising rays (gamma and e-beam) and ethylene oxide.

IONISOS Acquires Leoni Studer Hard

Provider of cold sterilisation services in France and Spain IONISOS has announced it has completed the acquisition of Leoni Studer Hard from Leoni Group.

Ionisos to Attend A3P International Congress

Ionisos, one of the first companies in the world to have put ionising rays to good use for the sterilisation of medical devices, will be attending the A3P - International Congress in Biarritz, France, which is being held on 19-21 October 2010. Visit us at the congress to find out more a

IONISOS Modernization

To face the growth of its market, Ionisos's plant in Dagneux has been modernized and production will now be automated. The investment will allow a 30% increase in Dagneux's output, as well as profits of quality and productivity related to the handling of the parcels. Treatment times will be red

Ionisos Headquarters

13, chemin du Pontet

69 380 Civrieux d’Azergues


IONISOS – Usine Gamma

Parc dombes

Cotière Activités

01120 Dagneux


Ionisos Iberica - E-Beam Plant

Pol. Industrial Tarancón Sur - C/ Rocinante, parcela 50

16400 Tarancón (Cuenca)



Ionisos Baltics - Gamma Plant

Kurvi tee 406a

Alliku 76401 Saue vald



Ionisos Deutschland - E-Beam Plant

Nikolaux-Otto - Straße 5

02625 Bautzen



13, zone industrielle du pontet

69380 Civrieux d’Azergues



ZI de Montifaut

31, rue René Truhaut

85700 Pouzauges


Ionisos - Gamma Plant

ZI de l’Aubrée

72300 Sablé-sur-Sarthe


Ionisos – Usine E-Beam


10500 Brienne-le-Chateau


STERYLENE : Ionisos – Usine EO


ZI les Montoires

45500 Gien


Ionisos Italia

Via Pompei


20900 Monza MB


Sterylene Italia

Via Pompei


20900 Monza MB