10X Genomics has patented a microfluidic system for encapsulating reagents in droplets for biological analyses. The system includes fluid sources, an agitating component, and a flow control system to generate droplets containing microcapsules. This innovation enhances efficiency in biological characterization processes. GlobalData’s report on 10X Genomics gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on 10X Genomics, ChIP-seq sequencing was a key innovation area identified from patents. 10X Genomics's grant share as of May 2024 was 15%. Grant share is based on the ratio of number of grants to total number of patents.
Microfluidic system for encapsulated reagents generation and partitioning
A recently granted patent (Publication Number: US12005454B2) discloses a novel microfluidic system designed for generating droplets containing microcapsules. The system comprises a first fluid source with an aqueous fluid and microcapsules, an agitating component, a second fluid source with an immiscible fluid, and a droplet generation junction. A flow control system, including independently controlled pressure sources, facilitates the flow of the first and second fluids to meet at the junction, resulting in the generation of droplets containing microcapsules that flow along a designated channel. Additionally, the system can incorporate a third fluid source with an additional aqueous fluid, further expanding its capabilities for creating mixtures of fluids.
Furthermore, the microfluidic system described in the patent includes features such as an agitating component to prevent settling of microcapsules, the encapsulation of reagents within the microcapsules, and the use of barcode sequences as reagents. The system's versatility is enhanced by the ability to control the flow of multiple fluids independently, ensuring precise manipulation of droplet generation and fluid mixing processes. Additionally, the agitating component can be piezoelectric, acoustic, or mechanical, providing flexibility in the system's design and operation. Overall, the patented microfluidic system offers a sophisticated and efficient solution for generating droplets containing microcapsules and conducting various fluid-based experiments with high precision and control.
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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.
