Fresenius Kabi has been granted a patent for a system that concentrates cells using a syringe with a filter for sterility maintenance. The syringe holder fits into a centrifuge rotor, allowing the plunger to be actuated by air pressure or vacuum. GlobalData’s report on Fresenius Kabi gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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Data Insights Fresenius Kabi AG - Company Profile

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According to GlobalData’s company profile on Fresenius Kabi, was a key innovation area identified from patents. Fresenius Kabi's grant share as of February 2024 was 64%. Grant share is based on the ratio of number of grants to total number of patents.

Cell concentration system with syringe, filter, and centrifuge compatibility

Source: United States Patent and Trademark Office (USPTO). Credit: Fresenius Kabi AG

A recently granted patent (Publication Number: US11911553B2) discloses a system and method for concentrating cells using a syringe-based approach. The system includes a syringe with a lumen, a filter for maintaining sterility, a cap with a vent, and a syringe holder designed to fit into a centrifuge rotor. The method involves mounting the syringe in the holder, centrifuging it to separate cells, expressing off the supernatant, and resuspending the pelletized cells in a desired volume of supernatant. The plunger in the syringe is actuated by air pressure and vacuum to facilitate the process efficiently.

Furthermore, the patent details various aspects of the system and method, such as the capacity of the syringe, the configuration of the syringe holder, and the use of an actuator handle for plunger actuation. The method also includes steps for drawing and expressing off the cell suspension, as well as preparing the cells for resuspension. The patent emphasizes the importance of maintaining sterility throughout the process and provides specific pore size requirements for the filter. Overall, the system and method offer a comprehensive approach to cell concentration, particularly suitable for applications involving red blood cells, white blood cells, and platelets, among others.

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.