Guerbet has filed a patent for an embolization microcatheter designed for peripheral artery embolization. The microcatheter features an elongated tubular member with a distal end measuring 150-500 mm in length and less than 0.8 mm in outer diameter. The tubular member consists of multiple sections, each with a length of 5-150 mm, and a wall composed of a braid, a polymer, and an inner liner. The polymer composition varies among the sections. The microcatheter also includes a distal tip measuring 1-3 mm in length, devoid of a braid, and extending between a proximal radiopaque marker and the distal end opening. The patent claim further specifies the dimensions and characteristics of the microcatheter. GlobalData’s report on Guerbet gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Guerbet, nanorobotics was a key innovation area identified from patents. Guerbet's grant share as of September 2023 was 54%. Grant share is based on the ratio of number of grants to total number of patents.

Embolization microcatheter for peripheral artery embolization

Source: United States Patent and Trademark Office (USPTO). Credit: Guerbet SA

A recently filed patent (Publication Number: US20230302254A1) describes an embolization microcatheter designed for the embolization of peripheral arteries. The microcatheter consists of an elongated tubular member with a distal end opening and a diameter of 0.7 mm or less. The tubular member is divided into multiple sections, each ranging from 5 mm to 120 mm in length. The wall of each section is composed of a braid, a polymer coating, and an inner liner. The thickness of the wall is less than 100 microns. The distal tip of the microcatheter, which extends between a radiopaque marker and the distal end opening, does not contain a braid.

The inner lumen of the distal end of the microcatheter ranges from 0.3 mm to 0.7 mm, while the inner lumen of the distal tip is below 0.5 mm. The thickness of the wall is less than 90 microns. The braid used in the microcatheter is made of tungsten wires with a diameter of 15-20 microns and a picks per inch (PPI) of 150-220. The microcatheter consists of at least 5 sections, with the distal most section measuring 5-15 mm in length. The distal radiopaque marker is a metal marker band.

In some embodiments, the distal most section of the microcatheter includes a filter formed in the wall, consisting of a plurality of side openings distributed in at least 5 circumferential rings. The side openings are spaced apart by 100 microns - 200 microns. The openings can be in the form of axial slits, with a length of about 100-150 microns and a height of about 20-40 microns. The distal most circumferential ring of the filter section is positioned about 2-6 mm proximally to the distal end opening. The number of side openings in each circumferential ring can vary, with the proximal most ring having fewer openings than the rings distal to it. The side openings in the proximal most circumferential section can be circumferentially shifted relative to the neighboring section.

Overall, this patent describes an embolization microcatheter with specific design features that make it suitable for use in peripheral artery embolization procedures. The microcatheter's small diameter, thin wall, and inclusion of a filter section with side openings provide precise and effective embolization capabilities.

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies