InspireMD has been granted a patent for a self-adjusting stent assembly. The stent assembly is designed to expand within a range of diameters (5.5mm to 9mm) based on the estimated diameter of the body lumen. It applies a chronic radial force to the lumen wall, with a maximum force of 0.33 N/mm. The stent assembly can act as either a straight or tapered stent and includes a knitted stent jacket with specific dimensions. GlobalData’s report on InspireMD gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on InspireMD, prosthetic cardiac valves was a key innovation area identified from patents. InspireMD's grant share as of June 2023 was 1%. Grant share is based on the ratio of number of grants to total number of patents.

Self-adjusting stent assembly for body lumen with specific diameter

Source: United States Patent and Trademark Office (USPTO). Credit: InspireMD Inc

A recently granted patent (Publication Number: US11684498B2) describes a stent assembly that can be used in various body lumens. The stent assembly includes an expansible stent that can expand from an initial crimped diameter to a range of expanded diameters between 5.5 millimeters and 9 millimeters. The stent assembly can act as either a straight stent or a tapered stent and can adapt to the diameter of the body lumen it is deployed in, even if the lumen has a non-uniform diameter. The stent assembly applies a chronic radial force to the wall of the body lumen to provide support.

The stent assembly also includes a knitted stent jacket made of an expansible mesh structure formed from fibers with a diameter between about 7 micrometers and about 40 micrometers. The mesh structure has a retracted state associated with the initial crimped diameter and a deployed state associated with the expanded diameter. The mesh structure has apertures with a minimum center dimension greater than about 100 micrometers and no more than about 300 micrometers in the deployed state. The thickness of the mesh structure ranges from greater than about 12.5 micrometers to no more than about 100 micrometers.

The expansible stent in the assembly can be constructed from a metal, such as nitinol. When expanded to a diameter of 5.5 millimeters, the stent assembly applies a radial force of less than about 0.33 N/mm, which is considered acceptable and does not unduly stress the walls of the lumen. When expanded to a diameter of 9 millimeters, the stent assembly applies a radial force of at least 50% of the radial force it applies when expanded to 5.5 millimeters.

The patent also describes methods of using the stent assembly for stenting body lumens. The methods involve estimating the diameter of the lumen, selecting the appropriate stent assembly based on the target expanded diameter, and implanting the stent assembly in the lumen. The stent assembly is designed to expand and apply a chronic radial force to the lumen wall. The methods also include instructions for stenting lesions and dealing with varying lumen diameters.

Overall, this patent describes a stent assembly with an expansible stent and a knitted stent jacket that can be used in various body lumens. The assembly can adapt to different lumen diameters and provide support without unduly stressing the lumen walls. The patent also includes methods for using the stent assembly in stenting procedures.

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.