Seegene has been granted a patent for a novel method of extracting nucleic acids using a magnet module and a cover module. The invention allows for automated extraction of nucleic acids using magnetic beads, resulting in higher levels of automation, reduced costs, and shorter reaction times compared to conventional methods. The method involves coupling the modules with moving modules in an apparatus, lowering the cover module to insert the tube into a vessel, and moving the rod and tube out of the vessel for extraction. GlobalData’s report on Seegene gives a 360-degree view of the company including its patenting strategy. Buy the report here.
According to GlobalData’s company profile on Seegene, AI-assisted drug screening was a key innovation area identified from patents. Seegene's grant share as of June 2023 was 1%. Grant share is based on the ratio of number of grants to total number of patents.
Automated method for extracting nucleic acids using magnetic beads
A recently granted patent (Publication Number: US11674971B2) describes a method for extracting nucleic acids from a sample using a magnet module and a cover module in an apparatus with moving modules. The magnet module includes a rod with magnetic force-generating material for collecting magnetic beads, a rod-supporting part, and a first coupling part to connect with the first moving module. The cover module consists of a tube to guide the rod, a tube-supporting part, and a second coupling part to connect with the second moving module. The method involves coupling the moving modules with the magnet and cover modules, moving them to an upper space of a vessel, lowering the cover module to locate the tube into the vessel's inner space, moving the cover module up and down, inserting the rod into the tube by lowering the magnet module, and lifting both the magnet and cover modules to remove the rod and tube from the vessel.
The patent also mentions that the coupling of the moving modules with the magnet and cover modules involves positioning them and connecting them at that position. Additionally, the method involves parallel actions of lowering the cover module to locate the tube and lowering the magnet module to locate the rod, with the cover module moving up and down after the rod is removed from the vessel. The vessel contains a sample, a lysis reagent, and magnetic beads. The method can also be used for washing or elution processes, in addition to the extraction process.
The described apparatus is an automated liquid handling apparatus, and at least one of the moving modules includes a transport mechanism and a multi-function probe. The moving modules can be a pipettor module or a gripper module.
In summary, the granted patent outlines a method for extracting nucleic acids from a sample using a magnet module and a cover module in an automated liquid handling apparatus. The method involves specific movements and couplings of the modules, as well as the use of a vessel containing a sample, lysis reagent, and magnetic beads. The method can be used for extraction, washing, and elution processes.